Brucellosis in older person: a case report from Qatar

<h3>Background</h3><p dir="ltr">Brucellosis is a multisystem disease with a broad spectrum of non-specific symptoms that generally occur within three weeks but sometimes up to 3 months after inoculation. Human brucellosis is quite uncommon in Elderly in Qatar.</p>&l...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Hanadi Khamis Al Hamad (21406964) (author)
مؤلفون آخرون: Navas Nadukkandiyil (18174292) (author), Mohammed Al Husami (21406967) (author), Hebatullah Ahmed Abdelgawad (21406970) (author), Sanjeevikumar Meenakshisundaram (21406973) (author), Osman Bashir Nemeri (21406976) (author)
منشور في: 2022
الموضوعات:
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author Hanadi Khamis Al Hamad (21406964)
author2 Navas Nadukkandiyil (18174292)
Mohammed Al Husami (21406967)
Hebatullah Ahmed Abdelgawad (21406970)
Sanjeevikumar Meenakshisundaram (21406973)
Osman Bashir Nemeri (21406976)
author2_role author
author
author
author
author
author_facet Hanadi Khamis Al Hamad (21406964)
Navas Nadukkandiyil (18174292)
Mohammed Al Husami (21406967)
Hebatullah Ahmed Abdelgawad (21406970)
Sanjeevikumar Meenakshisundaram (21406973)
Osman Bashir Nemeri (21406976)
author_role author
dc.creator.none.fl_str_mv Hanadi Khamis Al Hamad (21406964)
Navas Nadukkandiyil (18174292)
Mohammed Al Husami (21406967)
Hebatullah Ahmed Abdelgawad (21406970)
Sanjeevikumar Meenakshisundaram (21406973)
Osman Bashir Nemeri (21406976)
dc.date.none.fl_str_mv 2022-10-28T09:00:00Z
dc.identifier.none.fl_str_mv 10.1080/13685538.2022.2138851
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Brucellosis_in_older_person_a_case_report_from_Qatar/29126741
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Clinical sciences
Brucellosis
PUO
elderly
Qatar
dc.title.none.fl_str_mv Brucellosis in older person: a case report from Qatar
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Background</h3><p dir="ltr">Brucellosis is a multisystem disease with a broad spectrum of non-specific symptoms that generally occur within three weeks but sometimes up to 3 months after inoculation. Human brucellosis is quite uncommon in Elderly in Qatar.</p><h3>Case report</h3><p dir="ltr">This report describes a case of Brucellosis in acute geriatric unit under Rumailah Hospital in Qatar. The patient was an 81-year-old Qatari Gentle man, functionally able to walk with minimal assistance and had mild cognitive impairment who presented with high-grade fever with chills, anorexia, low back pain and arthralgia for 10 days. The above complaints occurred often for 1 month and had fever intermittently. Lab investigations revealed as high CRP 117 mg/l, low Hb 9.1 g/dl and mild elevation in ALP (151 µ/l) with normal leukocyte and platelet count. His blood culture positive for Brucella melitensis with high brucella Antibody titter 1:1280. The diagnosis made as Brucellosis.</p><h3>Discussion</h3><p dir="ltr">The clinical manifestations of Brucellosis are fever, night sweating, chills, arthralgia and loss of appetite. It seems pyrexia of unknown origin without other symptoms is most common presentation of Brucellosis in old age. The confirmation of Brucellosis made with serological tests, with significantly high titer, in the presence or absence of blood culture. Brucella antibody titers (≥1:160) are suggestive of active infection. Anemia and raised CRP and liver enzymes were the most prominent laboratory abnormalities in our patients. Previous study from Qatar reported that 41.7% had a history of raw milk consumption and 12.5% had a history of animal contact. The objectives of Brucellosis treatment include the prevention of complications and relapse.</p><h3>Conclusion</h3><p dir="ltr">Our case presented with classical symptoms and received appropriate treatment on time. However, atypical clinical presentation and lack of specific history taking can delay diagnosis and treatment; it leads to serious clinical disease progression with increased complications. From this case study, we would contribute to optimal assessment and to keep differential diagnosis for unknown cause of fever can be Brucellosis in geriatric population.</p><h2>Other Information</h2><p dir="ltr">Published in: The Aging Male<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1080/13685538.2022.2138851" target="_blank">https://dx.doi.org/10.1080/13685538.2022.2138851</a></p>
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network_acronym_str Manara2
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spelling Brucellosis in older person: a case report from QatarHanadi Khamis Al Hamad (21406964)Navas Nadukkandiyil (18174292)Mohammed Al Husami (21406967)Hebatullah Ahmed Abdelgawad (21406970)Sanjeevikumar Meenakshisundaram (21406973)Osman Bashir Nemeri (21406976)Biomedical and clinical sciencesClinical sciencesBrucellosisPUOelderlyQatar<h3>Background</h3><p dir="ltr">Brucellosis is a multisystem disease with a broad spectrum of non-specific symptoms that generally occur within three weeks but sometimes up to 3 months after inoculation. Human brucellosis is quite uncommon in Elderly in Qatar.</p><h3>Case report</h3><p dir="ltr">This report describes a case of Brucellosis in acute geriatric unit under Rumailah Hospital in Qatar. The patient was an 81-year-old Qatari Gentle man, functionally able to walk with minimal assistance and had mild cognitive impairment who presented with high-grade fever with chills, anorexia, low back pain and arthralgia for 10 days. The above complaints occurred often for 1 month and had fever intermittently. Lab investigations revealed as high CRP 117 mg/l, low Hb 9.1 g/dl and mild elevation in ALP (151 µ/l) with normal leukocyte and platelet count. His blood culture positive for Brucella melitensis with high brucella Antibody titter 1:1280. The diagnosis made as Brucellosis.</p><h3>Discussion</h3><p dir="ltr">The clinical manifestations of Brucellosis are fever, night sweating, chills, arthralgia and loss of appetite. It seems pyrexia of unknown origin without other symptoms is most common presentation of Brucellosis in old age. The confirmation of Brucellosis made with serological tests, with significantly high titer, in the presence or absence of blood culture. Brucella antibody titers (≥1:160) are suggestive of active infection. Anemia and raised CRP and liver enzymes were the most prominent laboratory abnormalities in our patients. Previous study from Qatar reported that 41.7% had a history of raw milk consumption and 12.5% had a history of animal contact. The objectives of Brucellosis treatment include the prevention of complications and relapse.</p><h3>Conclusion</h3><p dir="ltr">Our case presented with classical symptoms and received appropriate treatment on time. However, atypical clinical presentation and lack of specific history taking can delay diagnosis and treatment; it leads to serious clinical disease progression with increased complications. From this case study, we would contribute to optimal assessment and to keep differential diagnosis for unknown cause of fever can be Brucellosis in geriatric population.</p><h2>Other Information</h2><p dir="ltr">Published in: The Aging Male<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1080/13685538.2022.2138851" target="_blank">https://dx.doi.org/10.1080/13685538.2022.2138851</a></p>2022-10-28T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1080/13685538.2022.2138851https://figshare.com/articles/journal_contribution/Brucellosis_in_older_person_a_case_report_from_Qatar/29126741CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/291267412022-10-28T09:00:00Z
spellingShingle Brucellosis in older person: a case report from Qatar
Hanadi Khamis Al Hamad (21406964)
Biomedical and clinical sciences
Clinical sciences
Brucellosis
PUO
elderly
Qatar
status_str publishedVersion
title Brucellosis in older person: a case report from Qatar
title_full Brucellosis in older person: a case report from Qatar
title_fullStr Brucellosis in older person: a case report from Qatar
title_full_unstemmed Brucellosis in older person: a case report from Qatar
title_short Brucellosis in older person: a case report from Qatar
title_sort Brucellosis in older person: a case report from Qatar
topic Biomedical and clinical sciences
Clinical sciences
Brucellosis
PUO
elderly
Qatar