Transcriptome of Tumor-Infiltrating T Cells in Colorectal Cancer Patients Uncovered a Unique Gene Signature in CD4+ T Cells Associated with Poor Disease-Specific Survival

Transcriptome of Tumor-Infiltrating T Cells in Colorectal Cancer Patients Uncovered a Unique Gene Signature in CD4+ T Cells Associated with Poor Disease-Specific Survival

<p dir="ltr">Colorectal cancer (CRC) is influenced by infiltration of immune cell populations in the tumor microenvironment. While elevated levels of cytotoxic T cells are associated with improved prognosis, limited studies have reported associations between CD4<sup>+</sup&g...

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Main Author: Salman M. Toor (8854751) (author)
Other Authors: Varun Sasidharan Nair (5396393) (author), Reem Saleh (3513056) (author), Rowaida Z. Taha (8854754) (author), Khaled Murshed (8309781) (author), Mahmood Al-Dhaheri (9621035) (author), Mahwish Khawar (9621038) (author), Ayman A. Ahmed (18513762) (author), Mohamed A. Kurer (18513765) (author), Mohamed Abu Nada (8309784) (author), Eyad Elkord (5396390) (author)
Published: 2021
Subjects:
Biomedical and clinical sciences
Immunology
Oncology and carcinogenesis
colorectal cancer
tumor microenvironment
T cells
transcriptomics
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