Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight‐loss interventions
<p dir="ltr">Childhood obesity represents a significant public health concern, imposing a substantial burden on the healthcare system. Furthermore, weight‐loss programs often exhibit reduced effectiveness in adults who have a history of childhood obesity. Therefore, early interventio...
محفوظ في:
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| مؤلفون آخرون: | , , , , , , |
| منشور في: |
2024
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| الموضوعات: | |
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| _version_ | 1864513537971322880 |
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| author | Mohammad Al Zein (20090700) |
| author2 | Aishat Funmilayo Akomolafe (22391638) Fathima R. Mahmood (18560860) Ali Khrayzat (22391641) Amirhossein Sahebkar (1452028) Gianfranco Pintus (91638) Firas Kobeissy (307253) Ali H. Eid (5461829) |
| author2_role | author author author author author author author |
| author_facet | Mohammad Al Zein (20090700) Aishat Funmilayo Akomolafe (22391638) Fathima R. Mahmood (18560860) Ali Khrayzat (22391641) Amirhossein Sahebkar (1452028) Gianfranco Pintus (91638) Firas Kobeissy (307253) Ali H. Eid (5461829) |
| author_role | author |
| dc.creator.none.fl_str_mv | Mohammad Al Zein (20090700) Aishat Funmilayo Akomolafe (22391638) Fathima R. Mahmood (18560860) Ali Khrayzat (22391641) Amirhossein Sahebkar (1452028) Gianfranco Pintus (91638) Firas Kobeissy (307253) Ali H. Eid (5461829) |
| dc.date.none.fl_str_mv | 2024-07-23T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1111/obr.13807 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Leptin_is_a_potential_biomarker_of_childhood_obesity_and_an_indicator_of_the_effectiveness_of_weight_loss_interventions/30305716 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Medical biochemistry and metabolomics Nutrition and dietetics Paediatrics Health sciences Public health adipokines BMI metabolic disease obesity weight loss weight regain |
| dc.title.none.fl_str_mv | Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight‐loss interventions |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Childhood obesity represents a significant public health concern, imposing a substantial burden on the healthcare system. Furthermore, weight‐loss programs often exhibit reduced effectiveness in adults who have a history of childhood obesity. Therefore, early intervention against childhood obesity is imperative. Presently, the primary method for diagnosing childhood obesity relies on body mass index (BMI), yet this approach has inherent limitations. Leptin, a satiety hormone produced by adipocytes, holds promise as a superior tool for predicting both childhood and subsequent adulthood obesity. In this review, we elucidate the tools employed for assessing obesity in children, delve into the biological functions of leptin, and examine the factors governing its expression. Additionally, we discuss maternal and infantile leptin levels as predictors of childhood obesity. By exploring the relationship between leptin levels and weight loss, we present leptin as a potential indicator of the effectiveness of obesity interventions.</p><h2>Other Information</h2><p dir="ltr">Published in: Obesity Reviews<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1111/obr.13807" target="_blank">https://dx.doi.org/10.1111/obr.13807</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_1cd5109f0f8ac7982807c98a34335fde |
| identifier_str_mv | 10.1111/obr.13807 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30305716 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight‐loss interventionsMohammad Al Zein (20090700)Aishat Funmilayo Akomolafe (22391638)Fathima R. Mahmood (18560860)Ali Khrayzat (22391641)Amirhossein Sahebkar (1452028)Gianfranco Pintus (91638)Firas Kobeissy (307253)Ali H. Eid (5461829)Biomedical and clinical sciencesMedical biochemistry and metabolomicsNutrition and dieteticsPaediatricsHealth sciencesPublic healthadipokinesBMImetabolic diseaseobesityweight lossweight regain<p dir="ltr">Childhood obesity represents a significant public health concern, imposing a substantial burden on the healthcare system. Furthermore, weight‐loss programs often exhibit reduced effectiveness in adults who have a history of childhood obesity. Therefore, early intervention against childhood obesity is imperative. Presently, the primary method for diagnosing childhood obesity relies on body mass index (BMI), yet this approach has inherent limitations. Leptin, a satiety hormone produced by adipocytes, holds promise as a superior tool for predicting both childhood and subsequent adulthood obesity. In this review, we elucidate the tools employed for assessing obesity in children, delve into the biological functions of leptin, and examine the factors governing its expression. Additionally, we discuss maternal and infantile leptin levels as predictors of childhood obesity. By exploring the relationship between leptin levels and weight loss, we present leptin as a potential indicator of the effectiveness of obesity interventions.</p><h2>Other Information</h2><p dir="ltr">Published in: Obesity Reviews<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1111/obr.13807" target="_blank">https://dx.doi.org/10.1111/obr.13807</a></p>2024-07-23T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1111/obr.13807https://figshare.com/articles/journal_contribution/Leptin_is_a_potential_biomarker_of_childhood_obesity_and_an_indicator_of_the_effectiveness_of_weight_loss_interventions/30305716CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/303057162024-07-23T09:00:00Z |
| spellingShingle | Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight‐loss interventions Mohammad Al Zein (20090700) Biomedical and clinical sciences Medical biochemistry and metabolomics Nutrition and dietetics Paediatrics Health sciences Public health adipokines BMI metabolic disease obesity weight loss weight regain |
| status_str | publishedVersion |
| title | Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight‐loss interventions |
| title_full | Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight‐loss interventions |
| title_fullStr | Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight‐loss interventions |
| title_full_unstemmed | Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight‐loss interventions |
| title_short | Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight‐loss interventions |
| title_sort | Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight‐loss interventions |
| topic | Biomedical and clinical sciences Medical biochemistry and metabolomics Nutrition and dietetics Paediatrics Health sciences Public health adipokines BMI metabolic disease obesity weight loss weight regain |