A new perspective on cardiovascular drift during prolonged exercise

<p dir="ltr">Prolonged exercise induces cardiovascular drift, which is characterized by decreasing mean arterial pressure (MAP), stroke volume and heart rate increase. Cardiovascular drift has been debated for a long time. Although the exact mechanisms underlying cardiovascular drift...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Amine Souissi (9931616) (author)
مؤلفون آخرون: Monoem Haddad (5345357) (author), Ismail Dergaa (10775738) (author), Helmi Ben Saad (5643173) (author), Karim Chamari (441535) (author)
منشور في: 2021
الموضوعات:
الوسوم: إضافة وسم
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author Amine Souissi (9931616)
author2 Monoem Haddad (5345357)
Ismail Dergaa (10775738)
Helmi Ben Saad (5643173)
Karim Chamari (441535)
author2_role author
author
author
author
author_facet Amine Souissi (9931616)
Monoem Haddad (5345357)
Ismail Dergaa (10775738)
Helmi Ben Saad (5643173)
Karim Chamari (441535)
author_role author
dc.creator.none.fl_str_mv Amine Souissi (9931616)
Monoem Haddad (5345357)
Ismail Dergaa (10775738)
Helmi Ben Saad (5643173)
Karim Chamari (441535)
dc.date.none.fl_str_mv 2021-12-15T00:00:00Z
dc.identifier.none.fl_str_mv 10.1016/j.lfs.2021.120109
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/A_new_perspective_on_cardiovascular_drift_during_prolonged_exercise/24314365
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Pharmacology and pharmaceutical sciences
Cardiac-force
Cardiovascular drift
Heart rate
Oxidative stress
Vasodilation
FIFA Medical Centre of Excellence (Aspetar)
dc.title.none.fl_str_mv A new perspective on cardiovascular drift during prolonged exercise
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">Prolonged exercise induces cardiovascular drift, which is characterized by decreasing mean arterial pressure (MAP), stroke volume and heart rate increase. Cardiovascular drift has been debated for a long time. Although the exact mechanisms underlying cardiovascular drift are still unknown, two theories have been proposed. The first is that increased skin blood flow displaces blood volume from central circulation to the periphery, which reduces stroke volume. According to this theory, the rise in heart rate is presumably responding to the drop in stroke volume and MAP. The alternative theory is that an increase in heart rate is due to an increase in sympathetic nervous activity causing reducing time at diastole, and therefore stroke volume. It may be difficult to determine a single robust factor accounting for cardiovascular drift, due to the broad range of circumstances. The primary focus of this review is to elucidate our understanding of cardiovascular drift during prolonged exercise through nitric oxide and force-frequency relationship. We highlight for the very first time that cardiovascular drift (in some conditions and within a specific time period) may be considered as a protective strategy against potential damage that could be induced by the intense and prolonged contraction of the myocardium.</p><h2>Other Information</h2><p dir="ltr">Published in: Life Sciences<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.lfs.2021.120109" target="_blank">https://dx.doi.org/10.1016/j.lfs.2021.120109</a></p>
eu_rights_str_mv openAccess
id Manara2_1d501cb1c67e28d4470b6a6663cd4400
identifier_str_mv 10.1016/j.lfs.2021.120109
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/24314365
publishDate 2021
repository.mail.fl_str_mv
repository.name.fl_str_mv
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rights_invalid_str_mv CC BY 4.0
spelling A new perspective on cardiovascular drift during prolonged exerciseAmine Souissi (9931616)Monoem Haddad (5345357)Ismail Dergaa (10775738)Helmi Ben Saad (5643173)Karim Chamari (441535)Biological sciencesBiochemistry and cell biologyBiomedical and clinical sciencesCardiovascular medicine and haematologyPharmacology and pharmaceutical sciencesCardiac-forceCardiovascular driftHeart rateOxidative stressVasodilationFIFA Medical Centre of Excellence (Aspetar)<p dir="ltr">Prolonged exercise induces cardiovascular drift, which is characterized by decreasing mean arterial pressure (MAP), stroke volume and heart rate increase. Cardiovascular drift has been debated for a long time. Although the exact mechanisms underlying cardiovascular drift are still unknown, two theories have been proposed. The first is that increased skin blood flow displaces blood volume from central circulation to the periphery, which reduces stroke volume. According to this theory, the rise in heart rate is presumably responding to the drop in stroke volume and MAP. The alternative theory is that an increase in heart rate is due to an increase in sympathetic nervous activity causing reducing time at diastole, and therefore stroke volume. It may be difficult to determine a single robust factor accounting for cardiovascular drift, due to the broad range of circumstances. The primary focus of this review is to elucidate our understanding of cardiovascular drift during prolonged exercise through nitric oxide and force-frequency relationship. We highlight for the very first time that cardiovascular drift (in some conditions and within a specific time period) may be considered as a protective strategy against potential damage that could be induced by the intense and prolonged contraction of the myocardium.</p><h2>Other Information</h2><p dir="ltr">Published in: Life Sciences<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.lfs.2021.120109" target="_blank">https://dx.doi.org/10.1016/j.lfs.2021.120109</a></p>2021-12-15T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.lfs.2021.120109https://figshare.com/articles/journal_contribution/A_new_perspective_on_cardiovascular_drift_during_prolonged_exercise/24314365CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/243143652021-12-15T00:00:00Z
spellingShingle A new perspective on cardiovascular drift during prolonged exercise
Amine Souissi (9931616)
Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Pharmacology and pharmaceutical sciences
Cardiac-force
Cardiovascular drift
Heart rate
Oxidative stress
Vasodilation
FIFA Medical Centre of Excellence (Aspetar)
status_str publishedVersion
title A new perspective on cardiovascular drift during prolonged exercise
title_full A new perspective on cardiovascular drift during prolonged exercise
title_fullStr A new perspective on cardiovascular drift during prolonged exercise
title_full_unstemmed A new perspective on cardiovascular drift during prolonged exercise
title_short A new perspective on cardiovascular drift during prolonged exercise
title_sort A new perspective on cardiovascular drift during prolonged exercise
topic Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Pharmacology and pharmaceutical sciences
Cardiac-force
Cardiovascular drift
Heart rate
Oxidative stress
Vasodilation
FIFA Medical Centre of Excellence (Aspetar)