Immune thrombocytopenia relapse post covid-19 vaccine in young male patient
<p dir="ltr">Immune thrombocytopenic purpura (ITP) is a blood disorder in which antibodies coating platelets cause platelets destruction in the spleen with resultant low platelets count and an increased tendency for bleeding. Coronavirus disease 2019 (COVID-19) is an illness caused b...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , |
| منشور في: |
2021
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| الموضوعات: | |
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إضافة وسم
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| _version_ | 1864513552582180864 |
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| author | Hana Qasim (17151079) |
| author2 | Elrazi Ali (14777284) Mohamad A. Yassin (17151082) |
| author2_role | author author |
| author_facet | Hana Qasim (17151079) Elrazi Ali (14777284) Mohamad A. Yassin (17151082) |
| author_role | author |
| dc.creator.none.fl_str_mv | Hana Qasim (17151079) Elrazi Ali (14777284) Mohamad A. Yassin (17151082) |
| dc.date.none.fl_str_mv | 2021-11-17T00:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.idcr.2021.e01344 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Immune_thrombocytopenia_relapse_post_covid-19_vaccine_in_young_male_patient/24314317 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Cardiovascular medicine and haematology Pharmacology and pharmaceutical sciences ITP SARS-CoV-2 Pfizer vaccine Relapse |
| dc.title.none.fl_str_mv | Immune thrombocytopenia relapse post covid-19 vaccine in young male patient |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Immune thrombocytopenic purpura (ITP) is a blood disorder in which antibodies coating platelets cause platelets destruction in the spleen with resultant low platelets count and an increased tendency for bleeding. Coronavirus disease 2019 (COVID-19) is an illness caused by SARS-COV2; it was first identified in December/2019; though it mainly affects the respiratory system, multisystemic complications are identified. Several ITP cases post mRNA SARS-CoV-2 vaccines were reported, and different pathophysiology theories about the underlying pathophysiology were discussed, but only a few ITP relapse cases have been reported so far. We present a 28-year-old Asian male, a known patient of ITP and in partial remission for eighteen months, who presented to the emergency department with ITP relapse (platelets count of 1 × 10^3 /µL), four days after receiving the second dose of Pfizer SARS-CoV-2 vaccine, which required treatment with intravenous immunoglobulins and dexamethasone. We further discuss the preferred approach in ITP patients who are willing to receive the COVID-19 vaccine.</p><h2>Other Information</h2><p dir="ltr">Published in: IDCases<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.idcr.2021.e01344" target="_blank">https://dx.doi.org/10.1016/j.idcr.2021.e01344</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_1ffcc9e7e06244103fa3556bc224a081 |
| identifier_str_mv | 10.1016/j.idcr.2021.e01344 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/24314317 |
| publishDate | 2021 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Immune thrombocytopenia relapse post covid-19 vaccine in young male patientHana Qasim (17151079)Elrazi Ali (14777284)Mohamad A. Yassin (17151082)Biomedical and clinical sciencesCardiovascular medicine and haematologyPharmacology and pharmaceutical sciencesITPSARS-CoV-2Pfizer vaccineRelapse<p dir="ltr">Immune thrombocytopenic purpura (ITP) is a blood disorder in which antibodies coating platelets cause platelets destruction in the spleen with resultant low platelets count and an increased tendency for bleeding. Coronavirus disease 2019 (COVID-19) is an illness caused by SARS-COV2; it was first identified in December/2019; though it mainly affects the respiratory system, multisystemic complications are identified. Several ITP cases post mRNA SARS-CoV-2 vaccines were reported, and different pathophysiology theories about the underlying pathophysiology were discussed, but only a few ITP relapse cases have been reported so far. We present a 28-year-old Asian male, a known patient of ITP and in partial remission for eighteen months, who presented to the emergency department with ITP relapse (platelets count of 1 × 10^3 /µL), four days after receiving the second dose of Pfizer SARS-CoV-2 vaccine, which required treatment with intravenous immunoglobulins and dexamethasone. We further discuss the preferred approach in ITP patients who are willing to receive the COVID-19 vaccine.</p><h2>Other Information</h2><p dir="ltr">Published in: IDCases<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.idcr.2021.e01344" target="_blank">https://dx.doi.org/10.1016/j.idcr.2021.e01344</a></p>2021-11-17T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.idcr.2021.e01344https://figshare.com/articles/journal_contribution/Immune_thrombocytopenia_relapse_post_covid-19_vaccine_in_young_male_patient/24314317CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/243143172021-11-17T00:00:00Z |
| spellingShingle | Immune thrombocytopenia relapse post covid-19 vaccine in young male patient Hana Qasim (17151079) Biomedical and clinical sciences Cardiovascular medicine and haematology Pharmacology and pharmaceutical sciences ITP SARS-CoV-2 Pfizer vaccine Relapse |
| status_str | publishedVersion |
| title | Immune thrombocytopenia relapse post covid-19 vaccine in young male patient |
| title_full | Immune thrombocytopenia relapse post covid-19 vaccine in young male patient |
| title_fullStr | Immune thrombocytopenia relapse post covid-19 vaccine in young male patient |
| title_full_unstemmed | Immune thrombocytopenia relapse post covid-19 vaccine in young male patient |
| title_short | Immune thrombocytopenia relapse post covid-19 vaccine in young male patient |
| title_sort | Immune thrombocytopenia relapse post covid-19 vaccine in young male patient |
| topic | Biomedical and clinical sciences Cardiovascular medicine and haematology Pharmacology and pharmaceutical sciences ITP SARS-CoV-2 Pfizer vaccine Relapse |