Unveiling the nexus: The tumor microenvironment as a strategic frontier in viral cancers
<p dir="ltr"><u>Viral infections</u> are a significant factor in the etiology of various cancers, with the <u>tumor microenvironment</u> (TME) playing a crucial role in <u>disease progression</u>. This review delves into the complex interactions be...
محفوظ في:
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| منشور في: |
2024
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| الملخص: | <p dir="ltr"><u>Viral infections</u> are a significant factor in the etiology of various cancers, with the <u>tumor microenvironment</u> (TME) playing a crucial role in <u>disease progression</u>. This review delves into the complex interactions between viruses and the TME, highlighting how these interactions shape the course of viral cancers. We explore the distinct roles of <u>immune cells</u>, including T-cells, B-cells, macrophages, and dendritic cells, within the TME and their influence on cancer progression. The review also examines how viral <u>oncoproteins</u> manipulate the TME to promote immune evasion and tumor survival. Unraveling these mechanisms highlights the emerging paradigm of targeting the TME as a novel approach to cancer treatment. Our analysis provides insights into the dynamic interplay between viruses and the TME, offering a roadmap for innovative treatments that leverage the unique characteristics of viral cancers.</p><h2>Other Information</h2><p dir="ltr">Published in: Cytokine<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.cyto.2024.156827" target="_blank">https://dx.doi.org/10.1016/j.cyto.2024.156827</a></p> |
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