Unveiling the nexus: The tumor microenvironment as a strategic frontier in viral cancers
<p dir="ltr"><u>Viral infections</u> are a significant factor in the etiology of various cancers, with the <u>tumor microenvironment</u> (TME) playing a crucial role in <u>disease progression</u>. This review delves into the complex interactions be...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | |
| منشور في: |
2024
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| الموضوعات: | |
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إضافة وسم
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| _version_ | 1864513539419406336 |
|---|---|
| author | Queenie Fernandes (14557388) |
| author2 | Oginni Gbenga Folorunsho (22282675) |
| author2_role | author |
| author_facet | Queenie Fernandes (14557388) Oginni Gbenga Folorunsho (22282675) |
| author_role | author |
| dc.creator.none.fl_str_mv | Queenie Fernandes (14557388) Oginni Gbenga Folorunsho (22282675) |
| dc.date.none.fl_str_mv | 2024-12-07T12:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.cyto.2024.156827 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Unveiling_the_nexus_The_tumor_microenvironment_as_a_strategic_frontier_in_viral_cancers/30173377 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Oncology and carcinogenesis Oncoviruses Tumor microenvironment Viral cancers Immunotherapy Cancer immunology Therapeutic Cancer vaccines |
| dc.title.none.fl_str_mv | Unveiling the nexus: The tumor microenvironment as a strategic frontier in viral cancers |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr"><u>Viral infections</u> are a significant factor in the etiology of various cancers, with the <u>tumor microenvironment</u> (TME) playing a crucial role in <u>disease progression</u>. This review delves into the complex interactions between viruses and the TME, highlighting how these interactions shape the course of viral cancers. We explore the distinct roles of <u>immune cells</u>, including T-cells, B-cells, macrophages, and dendritic cells, within the TME and their influence on cancer progression. The review also examines how viral <u>oncoproteins</u> manipulate the TME to promote immune evasion and tumor survival. Unraveling these mechanisms highlights the emerging paradigm of targeting the TME as a novel approach to cancer treatment. Our analysis provides insights into the dynamic interplay between viruses and the TME, offering a roadmap for innovative treatments that leverage the unique characteristics of viral cancers.</p><h2>Other Information</h2><p dir="ltr">Published in: Cytokine<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.cyto.2024.156827" target="_blank">https://dx.doi.org/10.1016/j.cyto.2024.156827</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_22980f71f6bd1a640d00553255ea8462 |
| identifier_str_mv | 10.1016/j.cyto.2024.156827 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30173377 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Unveiling the nexus: The tumor microenvironment as a strategic frontier in viral cancersQueenie Fernandes (14557388)Oginni Gbenga Folorunsho (22282675)Biomedical and clinical sciencesClinical sciencesOncology and carcinogenesisOncovirusesTumor microenvironmentViral cancersImmunotherapyCancer immunologyTherapeuticCancer vaccines<p dir="ltr"><u>Viral infections</u> are a significant factor in the etiology of various cancers, with the <u>tumor microenvironment</u> (TME) playing a crucial role in <u>disease progression</u>. This review delves into the complex interactions between viruses and the TME, highlighting how these interactions shape the course of viral cancers. We explore the distinct roles of <u>immune cells</u>, including T-cells, B-cells, macrophages, and dendritic cells, within the TME and their influence on cancer progression. The review also examines how viral <u>oncoproteins</u> manipulate the TME to promote immune evasion and tumor survival. Unraveling these mechanisms highlights the emerging paradigm of targeting the TME as a novel approach to cancer treatment. Our analysis provides insights into the dynamic interplay between viruses and the TME, offering a roadmap for innovative treatments that leverage the unique characteristics of viral cancers.</p><h2>Other Information</h2><p dir="ltr">Published in: Cytokine<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.cyto.2024.156827" target="_blank">https://dx.doi.org/10.1016/j.cyto.2024.156827</a></p>2024-12-07T12:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.cyto.2024.156827https://figshare.com/articles/journal_contribution/Unveiling_the_nexus_The_tumor_microenvironment_as_a_strategic_frontier_in_viral_cancers/30173377CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/301733772024-12-07T12:00:00Z |
| spellingShingle | Unveiling the nexus: The tumor microenvironment as a strategic frontier in viral cancers Queenie Fernandes (14557388) Biomedical and clinical sciences Clinical sciences Oncology and carcinogenesis Oncoviruses Tumor microenvironment Viral cancers Immunotherapy Cancer immunology Therapeutic Cancer vaccines |
| status_str | publishedVersion |
| title | Unveiling the nexus: The tumor microenvironment as a strategic frontier in viral cancers |
| title_full | Unveiling the nexus: The tumor microenvironment as a strategic frontier in viral cancers |
| title_fullStr | Unveiling the nexus: The tumor microenvironment as a strategic frontier in viral cancers |
| title_full_unstemmed | Unveiling the nexus: The tumor microenvironment as a strategic frontier in viral cancers |
| title_short | Unveiling the nexus: The tumor microenvironment as a strategic frontier in viral cancers |
| title_sort | Unveiling the nexus: The tumor microenvironment as a strategic frontier in viral cancers |
| topic | Biomedical and clinical sciences Clinical sciences Oncology and carcinogenesis Oncoviruses Tumor microenvironment Viral cancers Immunotherapy Cancer immunology Therapeutic Cancer vaccines |