Skeletal, dentoalveolar and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients: A systematic review and frequentist network meta-analysis

<h3>Introduction</h3><p dir="ltr">This study aimed to assess the available evidence regarding the skeletal, dentoalveolar, and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients. </p><h3>Methods</h3><p dir=&qu...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Maged S. Alhammadi (14150757) (author)
مؤلفون آخرون: Fady Hussein Fahim (21435920) (author), Reem Hassan Kelani (21435923) (author), Areej Ali Alsaeedi (21435926) (author), Basmah Hakam Mahdi (21435929) (author), Najah Alhashimi (15235759) (author), Esam Halboub (6302024) (author), Abeer A. Almashraqi (12411222) (author)
منشور في: 2025
الموضوعات:
الوسوم: إضافة وسم
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_version_ 1864513547339300864
author Maged S. Alhammadi (14150757)
author2 Fady Hussein Fahim (21435920)
Reem Hassan Kelani (21435923)
Areej Ali Alsaeedi (21435926)
Basmah Hakam Mahdi (21435929)
Najah Alhashimi (15235759)
Esam Halboub (6302024)
Abeer A. Almashraqi (12411222)
author2_role author
author
author
author
author
author
author
author_facet Maged S. Alhammadi (14150757)
Fady Hussein Fahim (21435920)
Reem Hassan Kelani (21435923)
Areej Ali Alsaeedi (21435926)
Basmah Hakam Mahdi (21435929)
Najah Alhashimi (15235759)
Esam Halboub (6302024)
Abeer A. Almashraqi (12411222)
author_role author
dc.creator.none.fl_str_mv Maged S. Alhammadi (14150757)
Fady Hussein Fahim (21435920)
Reem Hassan Kelani (21435923)
Areej Ali Alsaeedi (21435926)
Basmah Hakam Mahdi (21435929)
Najah Alhashimi (15235759)
Esam Halboub (6302024)
Abeer A. Almashraqi (12411222)
dc.date.none.fl_str_mv 2025-03-10T09:00:00Z
dc.identifier.none.fl_str_mv 10.1016/j.jormas.2025.102312
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Skeletal_dentoalveolar_and_soft_tissue_effects_of_different_maxillary_expansion_appliances_in_cleft_lip_palate_patients_A_systematic_review_and_frequentist_network_meta-analysis/29163224
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Clinical sciences
Dentistry
Cleft palate
Dentoalveolar
Expansion appliance
Hyrax expander
Skeletal
dc.title.none.fl_str_mv Skeletal, dentoalveolar and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients: A systematic review and frequentist network meta-analysis
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Introduction</h3><p dir="ltr">This study aimed to assess the available evidence regarding the skeletal, dentoalveolar, and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients. </p><h3>Methods</h3><p dir="ltr">We assessed the effects of different maxillary expansion appliances on skeletal and dentoalveolar structures and soft tissues in cleft lip/palate patients. We searched the PubMed, Science Direct, Web of Science, Cochrane, and LILACS databases through September 2024; that investigation was augmented by a manual search. We focused on clinical trials and longitudinal studies, either retrospective or prospective. The outcomes of interest included skeletal, dentoalveolar, and soft tissue changes obtained from study models, cephalometric radiographs, or cone beam computed tomography. </p><h3>Results</h3><p dir="ltr">Of the 430 screened articles, only six satisfied our eligibility criteria and were included in the quantitative synthesis. These articles exhibited a moderate overall risk of bias. None of the appliances conferred better forward skeletal maxillary movement than the hyrax. The iMini-Molars (iMini-M) was the most effective appliance for increasing maxillary skeletal width (mean: 0.89 mm [range: 0.01–1.78]), with the hyrax following closely behind. The Haas appliance exhibited the largest inter-molar distance (mean: 4.76 mm [range: 2.53–6.99]), followed by the Differential opening appliance (EDO), iMini-M, and the hyrax. The fan-type appliance was the least effective at resisting maxillary premolar tipping (14.46° [2.60–26.32]), and the iMini-premolars (iMini-P) was the most effective at reducing molar tipping (-3.54° [-6.06– -1.02]). </p><h3>Conclusions</h3><p dir="ltr">Considering the limited number of studies and moderate risk of bias, the iMini-M was the most effective appliance at increasing maxillary skeletal width compared with the hyrax; the Haas achieved the largest inter-molar distance. The fan-type appliance excelled at resisting premolar tipping, and the iMini-P offered the best control for molar tipping. </p><h3>Registration</h3><p dir="ltr">The protocol for this systematic review was registered at the International Prospective Register of Systematic Reviews (PROSPERO, No.: CRD42023489536)</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Stomatology Oral and Maxillofacial Surgery<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jormas.2025.102312" target="_blank">https://dx.doi.org/10.1016/j.jormas.2025.102312</a></p>
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network_acronym_str Manara2
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oai_identifier_str oai:figshare.com:article/29163224
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spelling Skeletal, dentoalveolar and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients: A systematic review and frequentist network meta-analysisMaged S. Alhammadi (14150757)Fady Hussein Fahim (21435920)Reem Hassan Kelani (21435923)Areej Ali Alsaeedi (21435926)Basmah Hakam Mahdi (21435929)Najah Alhashimi (15235759)Esam Halboub (6302024)Abeer A. Almashraqi (12411222)Biomedical and clinical sciencesClinical sciencesDentistryCleft palateDentoalveolarExpansion applianceHyrax expanderSkeletal<h3>Introduction</h3><p dir="ltr">This study aimed to assess the available evidence regarding the skeletal, dentoalveolar, and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients. </p><h3>Methods</h3><p dir="ltr">We assessed the effects of different maxillary expansion appliances on skeletal and dentoalveolar structures and soft tissues in cleft lip/palate patients. We searched the PubMed, Science Direct, Web of Science, Cochrane, and LILACS databases through September 2024; that investigation was augmented by a manual search. We focused on clinical trials and longitudinal studies, either retrospective or prospective. The outcomes of interest included skeletal, dentoalveolar, and soft tissue changes obtained from study models, cephalometric radiographs, or cone beam computed tomography. </p><h3>Results</h3><p dir="ltr">Of the 430 screened articles, only six satisfied our eligibility criteria and were included in the quantitative synthesis. These articles exhibited a moderate overall risk of bias. None of the appliances conferred better forward skeletal maxillary movement than the hyrax. The iMini-Molars (iMini-M) was the most effective appliance for increasing maxillary skeletal width (mean: 0.89 mm [range: 0.01–1.78]), with the hyrax following closely behind. The Haas appliance exhibited the largest inter-molar distance (mean: 4.76 mm [range: 2.53–6.99]), followed by the Differential opening appliance (EDO), iMini-M, and the hyrax. The fan-type appliance was the least effective at resisting maxillary premolar tipping (14.46° [2.60–26.32]), and the iMini-premolars (iMini-P) was the most effective at reducing molar tipping (-3.54° [-6.06– -1.02]). </p><h3>Conclusions</h3><p dir="ltr">Considering the limited number of studies and moderate risk of bias, the iMini-M was the most effective appliance at increasing maxillary skeletal width compared with the hyrax; the Haas achieved the largest inter-molar distance. The fan-type appliance excelled at resisting premolar tipping, and the iMini-P offered the best control for molar tipping. </p><h3>Registration</h3><p dir="ltr">The protocol for this systematic review was registered at the International Prospective Register of Systematic Reviews (PROSPERO, No.: CRD42023489536)</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Stomatology Oral and Maxillofacial Surgery<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jormas.2025.102312" target="_blank">https://dx.doi.org/10.1016/j.jormas.2025.102312</a></p>2025-03-10T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.jormas.2025.102312https://figshare.com/articles/journal_contribution/Skeletal_dentoalveolar_and_soft_tissue_effects_of_different_maxillary_expansion_appliances_in_cleft_lip_palate_patients_A_systematic_review_and_frequentist_network_meta-analysis/29163224CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/291632242025-03-10T09:00:00Z
spellingShingle Skeletal, dentoalveolar and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients: A systematic review and frequentist network meta-analysis
Maged S. Alhammadi (14150757)
Biomedical and clinical sciences
Clinical sciences
Dentistry
Cleft palate
Dentoalveolar
Expansion appliance
Hyrax expander
Skeletal
status_str publishedVersion
title Skeletal, dentoalveolar and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients: A systematic review and frequentist network meta-analysis
title_full Skeletal, dentoalveolar and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients: A systematic review and frequentist network meta-analysis
title_fullStr Skeletal, dentoalveolar and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients: A systematic review and frequentist network meta-analysis
title_full_unstemmed Skeletal, dentoalveolar and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients: A systematic review and frequentist network meta-analysis
title_short Skeletal, dentoalveolar and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients: A systematic review and frequentist network meta-analysis
title_sort Skeletal, dentoalveolar and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients: A systematic review and frequentist network meta-analysis
topic Biomedical and clinical sciences
Clinical sciences
Dentistry
Cleft palate
Dentoalveolar
Expansion appliance
Hyrax expander
Skeletal