Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study

<div><p>Preterm birth (PTB) and early term birth (ETB) are associated with high risks of perinatal mortality and morbidity. While extreme to very PTBs have been extensively studied, studies on infants born at later stages of pregnancy, particularly late PTBs and ETBs, are lacking. In thi...

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Main Author: Salma Younes (6424865) (author)
Other Authors: Muthanna Samara (11619435) (author), Rana Al-Jurf (14150016) (author), Gheyath Nasrallah (11619444) (author), Sawsan Al-Obaidly (11619447) (author), Husam Salama (11619450) (author), Tawa Olukade (11619453) (author), Sara Hammuda (11619456) (author), Mohamed A. Ismail (418629) (author), Ghassan Abdoh (11619459) (author), Palli Valapila Abdulrouf (11619462) (author), Thomas Farrell (3933833) (author), Mai AlQubaisi (11619465) (author), Hilal Al Rifai (17039850) (author), Nader Al-Dewik (4166527) (author)
Published: 2021
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_version_ 1864513515378704384
author Salma Younes (6424865)
author2 Muthanna Samara (11619435)
Rana Al-Jurf (14150016)
Gheyath Nasrallah (11619444)
Sawsan Al-Obaidly (11619447)
Husam Salama (11619450)
Tawa Olukade (11619453)
Sara Hammuda (11619456)
Mohamed A. Ismail (418629)
Ghassan Abdoh (11619459)
Palli Valapila Abdulrouf (11619462)
Thomas Farrell (3933833)
Mai AlQubaisi (11619465)
Hilal Al Rifai (17039850)
Nader Al-Dewik (4166527)
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author_facet Salma Younes (6424865)
Muthanna Samara (11619435)
Rana Al-Jurf (14150016)
Gheyath Nasrallah (11619444)
Sawsan Al-Obaidly (11619447)
Husam Salama (11619450)
Tawa Olukade (11619453)
Sara Hammuda (11619456)
Mohamed A. Ismail (418629)
Ghassan Abdoh (11619459)
Palli Valapila Abdulrouf (11619462)
Thomas Farrell (3933833)
Mai AlQubaisi (11619465)
Hilal Al Rifai (17039850)
Nader Al-Dewik (4166527)
author_role author
dc.creator.none.fl_str_mv Salma Younes (6424865)
Muthanna Samara (11619435)
Rana Al-Jurf (14150016)
Gheyath Nasrallah (11619444)
Sawsan Al-Obaidly (11619447)
Husam Salama (11619450)
Tawa Olukade (11619453)
Sara Hammuda (11619456)
Mohamed A. Ismail (418629)
Ghassan Abdoh (11619459)
Palli Valapila Abdulrouf (11619462)
Thomas Farrell (3933833)
Mai AlQubaisi (11619465)
Hilal Al Rifai (17039850)
Nader Al-Dewik (4166527)
dc.date.none.fl_str_mv 2021-05-29T03:00:00Z
dc.identifier.none.fl_str_mv 10.3390/ijerph18115865
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Incidence_Risk_Factors_and_Outcomes_of_Preterm_and_Early_Term_Births_A_Population-Based_Register_Study/25867630
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Reproductive medicine
preterm birth (PTB)
prematurity
late preterm birth (Late PTB)
early term birth (ETB)
incidence
risk factors
outcomes
Qatar
dc.title.none.fl_str_mv Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <div><p>Preterm birth (PTB) and early term birth (ETB) are associated with high risks of perinatal mortality and morbidity. While extreme to very PTBs have been extensively studied, studies on infants born at later stages of pregnancy, particularly late PTBs and ETBs, are lacking. In this study, we aimed to assess the incidence, risk factors, and feto-maternal outcomes of PTB and ETB births in Qatar. We examined 15,865 singleton live births using 12-month retrospective registry data from the PEARL-Peristat Study. PTB and ETB incidence rates were 8.8% and 33.7%, respectively. PTB and ETB in-hospital mortality rates were 16.9% and 0.2%, respectively. Advanced maternal age, pre-gestational diabetes mellitus (PGDM), assisted pregnancies, and preterm history independently predicted both PTB and ETB, whereas chromosomal and congenital abnormalities were found to be independent predictors of PTB but not ETB. All groups of PTB and ETB were significantly associated with low birth weight (LBW), large for gestational age (LGA) births, caesarean delivery, and neonatal intensive care unit (NICU)/or death of neonate in labor room (LR)/operation theatre (OT). On the other hand, all or some groups of PTB were significantly associated with small for gestational age (SGA) births, Apgar < 7 at 1 and 5 min and in-hospital mortality. The findings of this study may serve as a basis for taking better clinical decisions with accurate assessment of risk factors, complications, and predictions of PTB and ETB.</p><p> </p></div><h2>Other Information</h2> <p> Published in: International Journal of Environmental Research and Public Health<br> License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/ijerph18115865" target="_blank">https://dx.doi.org/10.3390/ijerph18115865</a></p>
eu_rights_str_mv openAccess
id Manara2_26fd289b227fb56f665a36c60d963290
identifier_str_mv 10.3390/ijerph18115865
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/25867630
publishDate 2021
repository.mail.fl_str_mv
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rights_invalid_str_mv CC BY 4.0
spelling Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register StudySalma Younes (6424865)Muthanna Samara (11619435)Rana Al-Jurf (14150016)Gheyath Nasrallah (11619444)Sawsan Al-Obaidly (11619447)Husam Salama (11619450)Tawa Olukade (11619453)Sara Hammuda (11619456)Mohamed A. Ismail (418629)Ghassan Abdoh (11619459)Palli Valapila Abdulrouf (11619462)Thomas Farrell (3933833)Mai AlQubaisi (11619465)Hilal Al Rifai (17039850)Nader Al-Dewik (4166527)Biomedical and clinical sciencesReproductive medicinepreterm birth (PTB)prematuritylate preterm birth (Late PTB)early term birth (ETB)incidencerisk factorsoutcomesQatar<div><p>Preterm birth (PTB) and early term birth (ETB) are associated with high risks of perinatal mortality and morbidity. While extreme to very PTBs have been extensively studied, studies on infants born at later stages of pregnancy, particularly late PTBs and ETBs, are lacking. In this study, we aimed to assess the incidence, risk factors, and feto-maternal outcomes of PTB and ETB births in Qatar. We examined 15,865 singleton live births using 12-month retrospective registry data from the PEARL-Peristat Study. PTB and ETB incidence rates were 8.8% and 33.7%, respectively. PTB and ETB in-hospital mortality rates were 16.9% and 0.2%, respectively. Advanced maternal age, pre-gestational diabetes mellitus (PGDM), assisted pregnancies, and preterm history independently predicted both PTB and ETB, whereas chromosomal and congenital abnormalities were found to be independent predictors of PTB but not ETB. All groups of PTB and ETB were significantly associated with low birth weight (LBW), large for gestational age (LGA) births, caesarean delivery, and neonatal intensive care unit (NICU)/or death of neonate in labor room (LR)/operation theatre (OT). On the other hand, all or some groups of PTB were significantly associated with small for gestational age (SGA) births, Apgar < 7 at 1 and 5 min and in-hospital mortality. The findings of this study may serve as a basis for taking better clinical decisions with accurate assessment of risk factors, complications, and predictions of PTB and ETB.</p><p> </p></div><h2>Other Information</h2> <p> Published in: International Journal of Environmental Research and Public Health<br> License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/ijerph18115865" target="_blank">https://dx.doi.org/10.3390/ijerph18115865</a></p>2021-05-29T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.3390/ijerph18115865https://figshare.com/articles/journal_contribution/Incidence_Risk_Factors_and_Outcomes_of_Preterm_and_Early_Term_Births_A_Population-Based_Register_Study/25867630CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/258676302021-05-29T03:00:00Z
spellingShingle Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study
Salma Younes (6424865)
Biomedical and clinical sciences
Reproductive medicine
preterm birth (PTB)
prematurity
late preterm birth (Late PTB)
early term birth (ETB)
incidence
risk factors
outcomes
Qatar
status_str publishedVersion
title Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study
title_full Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study
title_fullStr Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study
title_full_unstemmed Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study
title_short Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study
title_sort Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study
topic Biomedical and clinical sciences
Reproductive medicine
preterm birth (PTB)
prematurity
late preterm birth (Late PTB)
early term birth (ETB)
incidence
risk factors
outcomes
Qatar