Exendin-4 promotes GSIS without increasing β-cell number through upregulation of glucose-sensing apparatus and mitochondrial oxidative phosphorylation machinery genes in hPSC-derived β-cells
<p><strong>Poster by Abdoulaye Diane, Razik Bin Abdul Mu-u-min, Asma Allouch, and Heba H. Al-Siddiqi (Hamad Bin Khalifa University)</strong></p> <p>Background: Impaired insulin secretion contributes to the pathogenesis of diabetes mellitus type 1 (T1DM) through autoimmu...
محفوظ في:
| المؤلف الرئيسي: | Abdoulaye Diane (14152749) (author) |
|---|---|
| مؤلفون آخرون: | Razik Bin Abdul Mu-u-min (15430008) (author), Asma Allouch (15430010) (author), Heba H Al-Siddiqi (12204889) (author) |
| منشور في: |
2023
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| الموضوعات: | |
| الوسوم: |
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مواد مشابهة
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β-cell mitochondria in diabetes mellitus: a missing puzzle piece in the generation of hPSC-derived pancreatic β-cells?
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Islets in the body are never flat: transitioning from two-dimensional (2D) monolayer culture to three-dimensional (3D) spheroid for better efficiency in the generation of functional hPSC-derived pancreatic β cells in vitro
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منشور في: (2023) -
Epigenetic memory as crucial contributing factor in directing the differentiation of human iPSC into pancreatic β-cells in vitro
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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
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حسب: Khaoula Errafii (10914446)
منشور في: (2022)