RFX3 is essential for the generation of functional human pancreatic islets from stem cells

RFX3 is essential for the generation of functional human pancreatic islets from stem cells

<h3>Aims/hypothesis</h3><p dir="ltr">The role of regulatory factor X 3 (RFX3) in human pancreatic islet development has not been explored. This study aims to investigate the function of RFX3 in human pancreatic islet development using human islet organoids derived from in...

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Bibliographic Details
Main Author: Bushra Memon (4792767) (author)
Other Authors: Noura Aldous (15429873) (author), Ahmed K. Elsayed (13275302) (author), Sadaf Ijaz (10992855) (author), Sikander Hayat (35163) (author), Essam M. Abdelalim (5768072) (author)
Published: 2025
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Medical biochemistry and metabolomics
Differentiation
Endocrine pancreas
Enterochromaffin cells
iPSC model
Transcription factor
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