The Effectiveness of Supervised Machine Learning in Screening and Diagnosing Voice Disorders: Systematic Review and Meta-analysis

<h3>Background</h3><p dir="ltr">When investigating voice disorders a series of processes are used when including voice screening and diagnosis. Both methods have limited standardized tests, which are affected by the clinician’s experience and subjective judgment. Machine...

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Main Author: Ghada Al-Hussain (18295426) (author)
Other Authors: Farag Shuweihdi (12573046) (author), Haitham Alali (18295429) (author), Mowafa Househ (9154124) (author), Alaa Abd-alrazaq (17058018) (author)
Published: 2022
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author Ghada Al-Hussain (18295426)
author2 Farag Shuweihdi (12573046)
Haitham Alali (18295429)
Mowafa Househ (9154124)
Alaa Abd-alrazaq (17058018)
author2_role author
author
author
author
author_facet Ghada Al-Hussain (18295426)
Farag Shuweihdi (12573046)
Haitham Alali (18295429)
Mowafa Househ (9154124)
Alaa Abd-alrazaq (17058018)
author_role author
dc.creator.none.fl_str_mv Ghada Al-Hussain (18295426)
Farag Shuweihdi (12573046)
Haitham Alali (18295429)
Mowafa Househ (9154124)
Alaa Abd-alrazaq (17058018)
dc.date.none.fl_str_mv 2022-10-14T03:00:00Z
dc.identifier.none.fl_str_mv 10.2196/38472
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/The_Effectiveness_of_Supervised_Machine_Learning_in_Screening_and_Diagnosing_Voice_Disorders_Systematic_Review_and_Meta-analysis/25532959
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Health sciences
Health services and systems
machine learning
voice disorders
systematic review
meta-analysis
diagnose
screening
mobile phone
dc.title.none.fl_str_mv The Effectiveness of Supervised Machine Learning in Screening and Diagnosing Voice Disorders: Systematic Review and Meta-analysis
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Background</h3><p dir="ltr">When investigating voice disorders a series of processes are used when including voice screening and diagnosis. Both methods have limited standardized tests, which are affected by the clinician’s experience and subjective judgment. Machine learning (ML) algorithms have been used as an objective tool in screening or diagnosing voice disorders. However, the effectiveness of ML algorithms in assessing and diagnosing voice disorders has not received sufficient scholarly attention.</p><h3>Objective</h3><p dir="ltr">This systematic review aimed to assess the effectiveness of ML algorithms in screening and diagnosing voice disorders.</p><h3>Methods</h3><p dir="ltr">An electronic search was conducted in 5 databases. Studies that examined the performance (accuracy, sensitivity, and specificity) of any ML algorithm in detecting pathological voice samples were included. Two reviewers independently selected the studies, extracted data from the included studies, and assessed the risk of bias. The methodological quality of each study was assessed using the Quality Assessment of Diagnostic Accuracy Studies 2 tool via RevMan 5 software (Cochrane Library). The characteristics of studies, population, and index tests were extracted, and meta-analyses were conducted to pool the accuracy, sensitivity, and specificity of ML techniques. The issue of heterogeneity was addressed by discussing possible sources and excluding studies when necessary.</p><h3>Results</h3><p dir="ltr">Of the 1409 records retrieved, 13 studies and 4079 participants were included in this review. A total of 13 ML techniques were used in the included studies, with the most common technique being least squares support vector machine. The pooled accuracy, sensitivity, and specificity of ML techniques in screening voice disorders were 93%, 96%, and 93%, respectively. Least squares support vector machine had the highest accuracy (99%), while the K-nearest neighbor algorithm had the highest sensitivity (98%) and specificity (98%). Quadric discriminant analysis achieved the lowest accuracy (91%), sensitivity (89%), and specificity (89%).</p><h3>Conclusions</h3><p dir="ltr">ML showed promising findings in the screening of voice disorders. However, the findings were not conclusive in diagnosing voice disorders owing to the limited number of studies that used ML for diagnostic purposes; thus, more investigations are needed. While it might not be possible to use ML alone as a substitute for current diagnostic tools, it may be used as a decision support tool for clinicians to assess their patients, which could improve the management process for assessment.</p><h3>Trial Registration</h3><p dir="ltr">PROSPERO CRD42020214438; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=214438</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Medical Internet Research<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2196/38472" target="_blank">https://dx.doi.org/10.2196/38472</a></p>
eu_rights_str_mv openAccess
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identifier_str_mv 10.2196/38472
network_acronym_str Manara2
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oai_identifier_str oai:figshare.com:article/25532959
publishDate 2022
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rights_invalid_str_mv CC BY 4.0
spelling The Effectiveness of Supervised Machine Learning in Screening and Diagnosing Voice Disorders: Systematic Review and Meta-analysisGhada Al-Hussain (18295426)Farag Shuweihdi (12573046)Haitham Alali (18295429)Mowafa Househ (9154124)Alaa Abd-alrazaq (17058018)Health sciencesHealth services and systemsmachine learningvoice disorderssystematic reviewmeta-analysisdiagnosescreeningmobile phone<h3>Background</h3><p dir="ltr">When investigating voice disorders a series of processes are used when including voice screening and diagnosis. Both methods have limited standardized tests, which are affected by the clinician’s experience and subjective judgment. Machine learning (ML) algorithms have been used as an objective tool in screening or diagnosing voice disorders. However, the effectiveness of ML algorithms in assessing and diagnosing voice disorders has not received sufficient scholarly attention.</p><h3>Objective</h3><p dir="ltr">This systematic review aimed to assess the effectiveness of ML algorithms in screening and diagnosing voice disorders.</p><h3>Methods</h3><p dir="ltr">An electronic search was conducted in 5 databases. Studies that examined the performance (accuracy, sensitivity, and specificity) of any ML algorithm in detecting pathological voice samples were included. Two reviewers independently selected the studies, extracted data from the included studies, and assessed the risk of bias. The methodological quality of each study was assessed using the Quality Assessment of Diagnostic Accuracy Studies 2 tool via RevMan 5 software (Cochrane Library). The characteristics of studies, population, and index tests were extracted, and meta-analyses were conducted to pool the accuracy, sensitivity, and specificity of ML techniques. The issue of heterogeneity was addressed by discussing possible sources and excluding studies when necessary.</p><h3>Results</h3><p dir="ltr">Of the 1409 records retrieved, 13 studies and 4079 participants were included in this review. A total of 13 ML techniques were used in the included studies, with the most common technique being least squares support vector machine. The pooled accuracy, sensitivity, and specificity of ML techniques in screening voice disorders were 93%, 96%, and 93%, respectively. Least squares support vector machine had the highest accuracy (99%), while the K-nearest neighbor algorithm had the highest sensitivity (98%) and specificity (98%). Quadric discriminant analysis achieved the lowest accuracy (91%), sensitivity (89%), and specificity (89%).</p><h3>Conclusions</h3><p dir="ltr">ML showed promising findings in the screening of voice disorders. However, the findings were not conclusive in diagnosing voice disorders owing to the limited number of studies that used ML for diagnostic purposes; thus, more investigations are needed. While it might not be possible to use ML alone as a substitute for current diagnostic tools, it may be used as a decision support tool for clinicians to assess their patients, which could improve the management process for assessment.</p><h3>Trial Registration</h3><p dir="ltr">PROSPERO CRD42020214438; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=214438</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Medical Internet Research<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2196/38472" target="_blank">https://dx.doi.org/10.2196/38472</a></p>2022-10-14T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.2196/38472https://figshare.com/articles/journal_contribution/The_Effectiveness_of_Supervised_Machine_Learning_in_Screening_and_Diagnosing_Voice_Disorders_Systematic_Review_and_Meta-analysis/25532959CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/255329592022-10-14T03:00:00Z
spellingShingle The Effectiveness of Supervised Machine Learning in Screening and Diagnosing Voice Disorders: Systematic Review and Meta-analysis
Ghada Al-Hussain (18295426)
Health sciences
Health services and systems
machine learning
voice disorders
systematic review
meta-analysis
diagnose
screening
mobile phone
status_str publishedVersion
title The Effectiveness of Supervised Machine Learning in Screening and Diagnosing Voice Disorders: Systematic Review and Meta-analysis
title_full The Effectiveness of Supervised Machine Learning in Screening and Diagnosing Voice Disorders: Systematic Review and Meta-analysis
title_fullStr The Effectiveness of Supervised Machine Learning in Screening and Diagnosing Voice Disorders: Systematic Review and Meta-analysis
title_full_unstemmed The Effectiveness of Supervised Machine Learning in Screening and Diagnosing Voice Disorders: Systematic Review and Meta-analysis
title_short The Effectiveness of Supervised Machine Learning in Screening and Diagnosing Voice Disorders: Systematic Review and Meta-analysis
title_sort The Effectiveness of Supervised Machine Learning in Screening and Diagnosing Voice Disorders: Systematic Review and Meta-analysis
topic Health sciences
Health services and systems
machine learning
voice disorders
systematic review
meta-analysis
diagnose
screening
mobile phone