Melatonin-induced symptomatic bradycardia in an otherwise healthy male: a case report
<p dir="ltr">Melatonin, a pineal gland hormone closely associated with the circadian rhythm, has been trending over the past years as an over-the-counter medication to aid with sleep disturbances. Although generally believed to be safe, recent studies show negative inotropic and chro...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | , , , , |
| Published: |
2024
|
| Subjects: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1864513540546625536 |
|---|---|
| author | Asim Alawad (19489015) |
| author2 | Wala Sati (19489018) Sara M I Ahmed (19489021) Moayed Elgassim (19489024) Mohamad Elgassim (19489027) Abderahman Balal (19489030) |
| author2_role | author author author author author |
| author_facet | Asim Alawad (19489015) Wala Sati (19489018) Sara M I Ahmed (19489021) Moayed Elgassim (19489024) Mohamad Elgassim (19489027) Abderahman Balal (19489030) |
| author_role | author |
| dc.creator.none.fl_str_mv | Asim Alawad (19489015) Wala Sati (19489018) Sara M I Ahmed (19489021) Moayed Elgassim (19489024) Mohamad Elgassim (19489027) Abderahman Balal (19489030) |
| dc.date.none.fl_str_mv | 2024-08-26T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1093/omcr/omae096 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Melatonin-induced_symptomatic_bradycardia_in_an_otherwise_healthy_male_a_case_report/30023872 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Pharmacology and pharmaceutical sciences melatonin bradycardia melatonin side-effect |
| dc.title.none.fl_str_mv | Melatonin-induced symptomatic bradycardia in an otherwise healthy male: a case report |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Melatonin, a pineal gland hormone closely associated with the circadian rhythm, has been trending over the past years as an over-the-counter medication to aid with sleep disturbances. Although generally believed to be safe, recent studies show negative inotropic and chronotropic effects on the heart rate and blood pressure in humans. Several studies suggested that melatonin induces cardiac vagal tone and affects heart rate and mean arterial pressure. Limited literature is currently available on the effects of melatonin beyond its sleep function. We present a case of a healthy 22-year-old male who visited the emergency department reporting palpitations and dizziness following the ingestion of 20 mg of melatonin. Subsequent examinations revealed marked bradycardia. Fortunately, the patient experienced spontaneous resolution of the bradycardia without necessitating intervention after a few hours of observation, and he was observed and discharged.</p><h2>Other Information</h2><p dir="ltr">Published in: Oxford Medical Case Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1093/omcr/omae096" target="_blank">https://dx.doi.org/10.1093/omcr/omae096</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_2a471a6aa7341c21fc3c4b64060e7505 |
| identifier_str_mv | 10.1093/omcr/omae096 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30023872 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Melatonin-induced symptomatic bradycardia in an otherwise healthy male: a case reportAsim Alawad (19489015)Wala Sati (19489018)Sara M I Ahmed (19489021)Moayed Elgassim (19489024)Mohamad Elgassim (19489027)Abderahman Balal (19489030)Biomedical and clinical sciencesCardiovascular medicine and haematologyClinical sciencesPharmacology and pharmaceutical sciencesmelatoninbradycardiamelatonin side-effect<p dir="ltr">Melatonin, a pineal gland hormone closely associated with the circadian rhythm, has been trending over the past years as an over-the-counter medication to aid with sleep disturbances. Although generally believed to be safe, recent studies show negative inotropic and chronotropic effects on the heart rate and blood pressure in humans. Several studies suggested that melatonin induces cardiac vagal tone and affects heart rate and mean arterial pressure. Limited literature is currently available on the effects of melatonin beyond its sleep function. We present a case of a healthy 22-year-old male who visited the emergency department reporting palpitations and dizziness following the ingestion of 20 mg of melatonin. Subsequent examinations revealed marked bradycardia. Fortunately, the patient experienced spontaneous resolution of the bradycardia without necessitating intervention after a few hours of observation, and he was observed and discharged.</p><h2>Other Information</h2><p dir="ltr">Published in: Oxford Medical Case Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1093/omcr/omae096" target="_blank">https://dx.doi.org/10.1093/omcr/omae096</a></p>2024-08-26T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1093/omcr/omae096https://figshare.com/articles/journal_contribution/Melatonin-induced_symptomatic_bradycardia_in_an_otherwise_healthy_male_a_case_report/30023872CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/300238722024-08-26T09:00:00Z |
| spellingShingle | Melatonin-induced symptomatic bradycardia in an otherwise healthy male: a case report Asim Alawad (19489015) Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Pharmacology and pharmaceutical sciences melatonin bradycardia melatonin side-effect |
| status_str | publishedVersion |
| title | Melatonin-induced symptomatic bradycardia in an otherwise healthy male: a case report |
| title_full | Melatonin-induced symptomatic bradycardia in an otherwise healthy male: a case report |
| title_fullStr | Melatonin-induced symptomatic bradycardia in an otherwise healthy male: a case report |
| title_full_unstemmed | Melatonin-induced symptomatic bradycardia in an otherwise healthy male: a case report |
| title_short | Melatonin-induced symptomatic bradycardia in an otherwise healthy male: a case report |
| title_sort | Melatonin-induced symptomatic bradycardia in an otherwise healthy male: a case report |
| topic | Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Pharmacology and pharmaceutical sciences melatonin bradycardia melatonin side-effect |