Human leukocyte antigen class II gene diversity tunes antibody repertoires to common pathogens

Human leukocyte antigen class II gene diversity tunes antibody repertoires to common pathogens

<div><p>Allelic diversity of human leukocyte antigen (HLA) class II genes may help maintain humoral immunity against infectious diseases. In this study, we investigated germline genetic variation in classical HLA class II genes and employed a systematic, unbiased approach to explore the...

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Bibliographic Details
Main Author: Taushif Khan (691254) (author)
Other Authors: Mahbuba Rahman (198499) (author), Ikhlak Ahmed (150200) (author), Fatima Al Ali (13210926) (author), Puthen Veettil Jithesh (12040358) (author), Nico Marr (349853) (author)
Published: 2022
Subjects:
Biomedical and clinical sciences
Immunology
human antibody repertoires
microbial infection
phage immunoprecipitation sequencing
human leukocyte antigen
major histocompatibility complex
polymorphisms
allelic diversity
association study
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