Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1

Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1

<h3>Background</h3><p dir="ltr">Pancreatic progenitors (PPs) co-expressing the two transcription factors (TFs) PDX1 and NKX6.1 are recognized as the indispensable precursors of functional pancreatic β cells. Here, we aimed to establish an efficient protocol for maximizing...

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Bibliographic Details
Main Author: Bushra Memon (4792767) (author)
Other Authors: Manale Karam (3619412) (author), Sara Al-Khawaga (4792761) (author), Essam M. Abdelalim (5768072) (author)
Published: 2018
Subjects:
Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Clinical sciences
Medical biotechnology
hPSCs
Beta cells
Diabetes
Differentiation
Transcription factors
Pancreatic epithelium
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