Management of chronic myeloid leukaemia: current treatment options, challenges, and future strategies

Management of chronic myeloid leukaemia: current treatment options, challenges, and future strategies

<p dir="ltr">Small molecule therapy is a critical component of targeted anticancer treatment, with tyrosine kinase inhibitors (TKIs) being the first compounds to treat the clonal Chronic Myelogenous Leukaemia (CML) translocation t (9;22) (q34; q11) effectively since 2001. TKIs, such...

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Main Author:	Salma Younes (6424865) (author)
Other Authors:	Mohamed A. Ismail (418629) (author), Rana Al-Jurf (14150016) (author), Ayah Ziyada (17931443) (author), Gheyath K. Nasrallah (9200525) (author), Palli Valapila Abdulrouf (11619462) (author), Mohamed Nagy (11874959) (author), Hatem Zayed (835448) (author), Thomas Farrell (3933833) (author), Claudio Sorio (212799) (author), Hisham Morsi (14152881) (author), M. Walid Qoronfleh (14153088) (author), Nader I. Al-Dewik (14152884) (author)
Published:	2023
Subjects:	Biological sciences Biochemistry and cell biology Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Oncology and carcinogenesis Pharmacology and pharmaceutical sciences Tyrosine kinase inhibitors (TKIs) BCR::ABL1; Chronic Myeloid Leukaemia (CML) resistance therapeutic targets cancer personalized medicine precision medicine
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