Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant Woman
<p dir="ltr">Rheumatic mitral stenosis (MS) with significant calcification presents challenges for both surgical and transcatheter interventions. Percutaneous balloon mitral valvuloplasty (PBMV) is often limited in these cases due to valve rigidity, increasing the risk of mitral regu...
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2025
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| author | Mhd Baraa Habib (11721774) |
| author2 | Cheikh Ahmed Aboulmaaly (22503647) Nazar Mohammed (22503650) Mohammed Al‐Hijji (22503653) |
| author2_role | author author author |
| author_facet | Mhd Baraa Habib (11721774) Cheikh Ahmed Aboulmaaly (22503647) Nazar Mohammed (22503650) Mohammed Al‐Hijji (22503653) |
| author_role | author |
| dc.creator.none.fl_str_mv | Mhd Baraa Habib (11721774) Cheikh Ahmed Aboulmaaly (22503647) Nazar Mohammed (22503650) Mohammed Al‐Hijji (22503653) |
| dc.date.none.fl_str_mv | 2025-06-02T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1002/ccd.31641 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Using_Shockwave_Lithotripsy_to_Treat_Severe_Calcified_Mitral_Stenosis_in_a_Pregnant_Woman/30455537 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Cardiovascular medicine and haematology Reproductive medicine angiographic/fluoroscopic IAF ‐ imaging MVD ‐ mitral valve disease MVPI ‐ mitral valve disease percutaneous intervention PREG ‐ pregnancy |
| dc.title.none.fl_str_mv | Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant Woman |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Rheumatic mitral stenosis (MS) with significant calcification presents challenges for both surgical and transcatheter interventions. Percutaneous balloon mitral valvuloplasty (PBMV) is often limited in these cases due to valve rigidity, increasing the risk of mitral regurgitation (MR). Transcatheter mitral valve lithotripsy (TMVL) is an emerging technique that uses sonic waves to disrupt calcification, enhancing valve pliability and PBMV outcomes. A 39‐year‐old woman, 18 weeks pregnant, with a history of rheumatic heart disease and prior surgical mitral commissurotomy, presented with palpitations, fatigue, and exertional breathlessness. She had severe MS (mitral valve area 0.8 cm²) and severe tricuspid regurgitation, with atrial fibrillation and rapid ventricular response. Due to a high Wilkins score, PBMV was attempted with a 28 mm Inoue balloon inflated to 28 mm, but was suboptimal due to significant valve rigidity. Adjunctive TMVL improved valve pliability, successfully reducing the mitral gradient and increasing valve area without worsening MR. The patient continued her pregnancy without complications. This case highlights TMVL as a promising adjunct to PBMV in severe calcified MS, particularly in high‐risk patients such as pregnant women. Further studies are needed to validate its efficacy and long‐term outcomes.</p><h2>Other Information</h2><p dir="ltr">Published in: Catheterization and Cardiovascular Interventions<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/ccd.31641" target="_blank">https://dx.doi.org/10.1002/ccd.31641</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_2d5f6831f96322d4f0a35cbd20bf59bd |
| identifier_str_mv | 10.1002/ccd.31641 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30455537 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant WomanMhd Baraa Habib (11721774)Cheikh Ahmed Aboulmaaly (22503647)Nazar Mohammed (22503650)Mohammed Al‐Hijji (22503653)Biomedical and clinical sciencesCardiovascular medicine and haematologyReproductive medicineangiographic/fluoroscopicIAF ‐ imagingMVD ‐ mitral valve diseaseMVPI ‐ mitral valve diseasepercutaneous interventionPREG ‐ pregnancy<p dir="ltr">Rheumatic mitral stenosis (MS) with significant calcification presents challenges for both surgical and transcatheter interventions. Percutaneous balloon mitral valvuloplasty (PBMV) is often limited in these cases due to valve rigidity, increasing the risk of mitral regurgitation (MR). Transcatheter mitral valve lithotripsy (TMVL) is an emerging technique that uses sonic waves to disrupt calcification, enhancing valve pliability and PBMV outcomes. A 39‐year‐old woman, 18 weeks pregnant, with a history of rheumatic heart disease and prior surgical mitral commissurotomy, presented with palpitations, fatigue, and exertional breathlessness. She had severe MS (mitral valve area 0.8 cm²) and severe tricuspid regurgitation, with atrial fibrillation and rapid ventricular response. Due to a high Wilkins score, PBMV was attempted with a 28 mm Inoue balloon inflated to 28 mm, but was suboptimal due to significant valve rigidity. Adjunctive TMVL improved valve pliability, successfully reducing the mitral gradient and increasing valve area without worsening MR. The patient continued her pregnancy without complications. This case highlights TMVL as a promising adjunct to PBMV in severe calcified MS, particularly in high‐risk patients such as pregnant women. Further studies are needed to validate its efficacy and long‐term outcomes.</p><h2>Other Information</h2><p dir="ltr">Published in: Catheterization and Cardiovascular Interventions<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/ccd.31641" target="_blank">https://dx.doi.org/10.1002/ccd.31641</a></p>2025-06-02T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1002/ccd.31641https://figshare.com/articles/journal_contribution/Using_Shockwave_Lithotripsy_to_Treat_Severe_Calcified_Mitral_Stenosis_in_a_Pregnant_Woman/30455537CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/304555372025-06-02T03:00:00Z |
| spellingShingle | Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant Woman Mhd Baraa Habib (11721774) Biomedical and clinical sciences Cardiovascular medicine and haematology Reproductive medicine angiographic/fluoroscopic IAF ‐ imaging MVD ‐ mitral valve disease MVPI ‐ mitral valve disease percutaneous intervention PREG ‐ pregnancy |
| status_str | publishedVersion |
| title | Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant Woman |
| title_full | Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant Woman |
| title_fullStr | Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant Woman |
| title_full_unstemmed | Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant Woman |
| title_short | Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant Woman |
| title_sort | Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant Woman |
| topic | Biomedical and clinical sciences Cardiovascular medicine and haematology Reproductive medicine angiographic/fluoroscopic IAF ‐ imaging MVD ‐ mitral valve disease MVPI ‐ mitral valve disease percutaneous intervention PREG ‐ pregnancy |