The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)

The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)

<p dir="ltr">Dysregulated epigenetic modifications are common in lung cancer but have been reversed using demethylating agent like 5-Aza-CdR. 5-Aza-CdR induces/upregulates the NY-ESO-1 antigen in lung cancer. Therefore, we investigated the molecular mechanisms accompanied with the ep...

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Main Author: Varghese P. Inchakalody (14557382) (author)
Other Authors: Shereena P. Hydrose (17821412) (author), Roopesh Krishnankutty (1297770) (author), Maysaloun Merhi (4246147) (author), Lubna Therachiyil (4246156) (author), Varun Sasidharan Nair (5396393) (author), Asma A. Elashi (17821415) (author), Abdul Q. Khan (14153247) (author), Sara Taleb (11264352) (author), Afsheen Raza (492657) (author), Zeenath Safira K.M. Yoosuf (17821418) (author), Queenie Fernandes (14557388) (author), Lobna Al-Zaidan (14557394) (author), Sarra Mestiri (14557379) (author), Nassiba Taib (14557385) (author), Takwa Bedhiafi (14153460) (author), Dina Moustafa (4253005) (author), Laila Assami (17821421) (author), Karama Makni Maalej (17821424) (author), Eyad Elkord (5396390) (author), Shahab Uddin (154400) (author), Ussama Al Homsi (14442150) (author), Said Dermime (79420) (author)
Published: 2023
Subjects:
Biological sciences
Biochemistry and cell biology
Genetics
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Oncology and carcinogenesis
Pharmacology and pharmaceutical sciences
Non small lung cancer
5 Aza-CdR
Epigenetic regulation
NY-ESO-1
Apoptosis
Intrinsic and extrinsic apoptotic pathway
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