Untargeted Metabolomic Profiling Reveals Differentially Expressed Serum Metabolites and Pathways in Type 2 Diabetes Patients with and without Cognitive Decline: A Cross-Sectional Study

Untargeted Metabolomic Profiling Reveals Differentially Expressed Serum Metabolites and Pathways in Type 2 Diabetes Patients with and without Cognitive Decline: A Cross-Sectional Study

<p dir="ltr">Diabetes is recognized as a risk factor for cognitive decline, but the underlying mechanisms remain elusive. We aimed to identify the metabolic pathways altered in diabetes-associated cognitive decline (DACD) using untargeted metabolomics. We conducted liquid chromatogra...

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Main Author: Neyla S. Al-Akl (10914449) (author)
Other Authors: Olfa Khalifa (10914452) (author), Georgios Ponirakis (803076) (author), Aijaz Parray (290256) (author), Marwan Ramadan (17499450) (author), Shafi Khan (17499453) (author), Mani Chandran (17499447) (author), Raheem Ayadathil (14150124) (author), Ahmed Elsotouhy (3853348) (author), Ahmed Own (6677990) (author), Hanadi Al Hamad (12229412) (author), Julie Decock (44558) (author), Nehad M. Alajez (7397276) (author), Omar Albagha (8977856) (author), Rayaz A. Malik (7372649) (author), Omar M. A. El-Agnaf (8809331) (author), Abdelilah Arredouani (10914455) (author)
Published: 2024
Subjects:
Biomedical and clinical sciences
Clinical sciences
Medical biochemistry and metabolomics
Neurosciences
dementia
mild cognitive impairment
type 2 diabetes
metabolomics
diabetes-associated cognitive decline
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