Severe cardiopulmonary complications of ketamine: Acute pulmonary Edema in a cardiac patient
<p dir="ltr">Ketamine use in the emergency department is more widespread than ever due to its favorable safety profile and combined analgesic and anesthetic properties. Its ability to stimulate the cardiovascular system via the sympathetic nervous system is particularly important, as...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | , |
| Published: |
2025
|
| Subjects: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1864513534232100864 |
|---|---|
| author | Tahir Shahzad (21842195) |
| author2 | Zain A Bhutta (22466815) Muhammad Abd Ur Rehman (17884283) |
| author2_role | author author |
| author_facet | Tahir Shahzad (21842195) Zain A Bhutta (22466815) Muhammad Abd Ur Rehman (17884283) |
| author_role | author |
| dc.creator.none.fl_str_mv | Tahir Shahzad (21842195) Zain A Bhutta (22466815) Muhammad Abd Ur Rehman (17884283) |
| dc.date.none.fl_str_mv | 2025-08-20T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1093/omcr/omaf063 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Severe_cardiopulmonary_complications_of_ketamine_Acute_pulmonary_Edema_in_a_cardiac_patient/30405676 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Pharmacology and pharmaceutical sciences ketamine procedural sedation Acute pulmonary edema cardiogenic shock |
| dc.title.none.fl_str_mv | Severe cardiopulmonary complications of ketamine: Acute pulmonary Edema in a cardiac patient |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Ketamine use in the emergency department is more widespread than ever due to its favorable safety profile and combined analgesic and anesthetic properties. Its ability to stimulate the cardiovascular system via the sympathetic nervous system is particularly important, as patients can develop hemodynamic instability. However, concerns remain regarding the risk of decompensated cardiac function due to extreme tachycardia and severely elevated systemic blood pressure. In this case, a middle-aged male with a known history of coronary artery disease and congestive heart failure deteriorated significantly after ketamine was administered for sedation to facilitate a computed tomography pulmonary angiogram. He developed acute pulmonary edema and cardiogenic shock, requiring mechanical ventilation and inotropic support. Therefore, it is advisable to use ketamine with caution in patients with underlying heart failure. Further research is needed to establish a causal relationship between ketamine and cardiac decompensation leading to cardiogenic shock and pulmonary edema in selected patients.</p><h2>Other Information</h2><p dir="ltr">Published in: Oxford Medical Case Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1093/omcr/omaf063" target="_blank">https://dx.doi.org/10.1093/omcr/omaf063</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_38e6a349fe3a9dbbf36dbac24e59ea4b |
| identifier_str_mv | 10.1093/omcr/omaf063 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30405676 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Severe cardiopulmonary complications of ketamine: Acute pulmonary Edema in a cardiac patientTahir Shahzad (21842195)Zain A Bhutta (22466815)Muhammad Abd Ur Rehman (17884283)Biomedical and clinical sciencesCardiovascular medicine and haematologyClinical sciencesPharmacology and pharmaceutical sciencesketamineprocedural sedationAcute pulmonary edemacardiogenic shock<p dir="ltr">Ketamine use in the emergency department is more widespread than ever due to its favorable safety profile and combined analgesic and anesthetic properties. Its ability to stimulate the cardiovascular system via the sympathetic nervous system is particularly important, as patients can develop hemodynamic instability. However, concerns remain regarding the risk of decompensated cardiac function due to extreme tachycardia and severely elevated systemic blood pressure. In this case, a middle-aged male with a known history of coronary artery disease and congestive heart failure deteriorated significantly after ketamine was administered for sedation to facilitate a computed tomography pulmonary angiogram. He developed acute pulmonary edema and cardiogenic shock, requiring mechanical ventilation and inotropic support. Therefore, it is advisable to use ketamine with caution in patients with underlying heart failure. Further research is needed to establish a causal relationship between ketamine and cardiac decompensation leading to cardiogenic shock and pulmonary edema in selected patients.</p><h2>Other Information</h2><p dir="ltr">Published in: Oxford Medical Case Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1093/omcr/omaf063" target="_blank">https://dx.doi.org/10.1093/omcr/omaf063</a></p>2025-08-20T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1093/omcr/omaf063https://figshare.com/articles/journal_contribution/Severe_cardiopulmonary_complications_of_ketamine_Acute_pulmonary_Edema_in_a_cardiac_patient/30405676CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/304056762025-08-20T09:00:00Z |
| spellingShingle | Severe cardiopulmonary complications of ketamine: Acute pulmonary Edema in a cardiac patient Tahir Shahzad (21842195) Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Pharmacology and pharmaceutical sciences ketamine procedural sedation Acute pulmonary edema cardiogenic shock |
| status_str | publishedVersion |
| title | Severe cardiopulmonary complications of ketamine: Acute pulmonary Edema in a cardiac patient |
| title_full | Severe cardiopulmonary complications of ketamine: Acute pulmonary Edema in a cardiac patient |
| title_fullStr | Severe cardiopulmonary complications of ketamine: Acute pulmonary Edema in a cardiac patient |
| title_full_unstemmed | Severe cardiopulmonary complications of ketamine: Acute pulmonary Edema in a cardiac patient |
| title_short | Severe cardiopulmonary complications of ketamine: Acute pulmonary Edema in a cardiac patient |
| title_sort | Severe cardiopulmonary complications of ketamine: Acute pulmonary Edema in a cardiac patient |
| topic | Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Pharmacology and pharmaceutical sciences ketamine procedural sedation Acute pulmonary edema cardiogenic shock |