Recent advances in stimuli-responsive drug release and targeting concepts using mesoporous silica nanoparticles
<p>Being a developed and promising approach, nanotechnology has attracted a lot of attention in biomedical and pharmaceutical therapy applications. Among nanostructured materials, mesoporous silica nanoparticles (MSNs) are effectively used as nanocarriers for drug delivery systems. MSNs can be...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , |
| منشور في: |
2022
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| الموضوعات: | |
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إضافة وسم
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| _version_ | 1864513567089229824 |
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| author | Ghada G. Abdo (14152380) |
| author2 | Moustafa M. Zagho (6421793) Ashraf Khalil (4591618) |
| author2_role | author author |
| author_facet | Ghada G. Abdo (14152380) Moustafa M. Zagho (6421793) Ashraf Khalil (4591618) |
| author_role | author |
| dc.creator.none.fl_str_mv | Ghada G. Abdo (14152380) Moustafa M. Zagho (6421793) Ashraf Khalil (4591618) |
| dc.date.none.fl_str_mv | 2022-11-22T21:16:06Z |
| dc.identifier.none.fl_str_mv | 10.1007/s42247-020-00109-x |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Recent_advances_in_stimuli-responsive_drug_release_and_targeting_concepts_using_mesoporous_silica_nanoparticles/21597909 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Pharmacology and pharmaceutical sciences Engineering Biomedical engineering Mesoporous silica nanoparticles Drug delivery Endogenous and exogenous stimuli Anticancer drug delivery Targeting |
| dc.title.none.fl_str_mv | Recent advances in stimuli-responsive drug release and targeting concepts using mesoporous silica nanoparticles |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p>Being a developed and promising approach, nanotechnology has attracted a lot of attention in biomedical and pharmaceutical therapy applications. Among nanostructured materials, mesoporous silica nanoparticles (MSNs) are effectively used as nanocarriers for drug delivery systems. MSNs can be tailored-designed by different synthetic techniques. Their morphological characteristics dictate the type of application of such materials. Recently, polymer-based materials have been employed to functionalize the MSNs surface. These modified nanocarriers are loaded with the drug and can unload their “cargo” upon exposure to either endogenous or exogenous types of stimuli. In this study, different targeting concepts, including passive, active, vascular, nuclear, and multistage targeting, are discussed.</p><h2>Other Information</h2> <p> Published in: Emergent Materials<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s42247-020-00109-x" target="_blank">http://dx.doi.org/10.1007/s42247-020-00109-x</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_3a3f5064b2f1ce767848181d63f39b03 |
| identifier_str_mv | 10.1007/s42247-020-00109-x |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/21597909 |
| publishDate | 2022 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Recent advances in stimuli-responsive drug release and targeting concepts using mesoporous silica nanoparticlesGhada G. Abdo (14152380)Moustafa M. Zagho (6421793)Ashraf Khalil (4591618)Biomedical and clinical sciencesPharmacology and pharmaceutical sciencesEngineeringBiomedical engineeringMesoporous silica nanoparticlesDrug deliveryEndogenous and exogenous stimuliAnticancer drug deliveryTargeting<p>Being a developed and promising approach, nanotechnology has attracted a lot of attention in biomedical and pharmaceutical therapy applications. Among nanostructured materials, mesoporous silica nanoparticles (MSNs) are effectively used as nanocarriers for drug delivery systems. MSNs can be tailored-designed by different synthetic techniques. Their morphological characteristics dictate the type of application of such materials. Recently, polymer-based materials have been employed to functionalize the MSNs surface. These modified nanocarriers are loaded with the drug and can unload their “cargo” upon exposure to either endogenous or exogenous types of stimuli. In this study, different targeting concepts, including passive, active, vascular, nuclear, and multistage targeting, are discussed.</p><h2>Other Information</h2> <p> Published in: Emergent Materials<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s42247-020-00109-x" target="_blank">http://dx.doi.org/10.1007/s42247-020-00109-x</a></p>2022-11-22T21:16:06ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s42247-020-00109-xhttps://figshare.com/articles/journal_contribution/Recent_advances_in_stimuli-responsive_drug_release_and_targeting_concepts_using_mesoporous_silica_nanoparticles/21597909CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/215979092022-11-22T21:16:06Z |
| spellingShingle | Recent advances in stimuli-responsive drug release and targeting concepts using mesoporous silica nanoparticles Ghada G. Abdo (14152380) Biomedical and clinical sciences Pharmacology and pharmaceutical sciences Engineering Biomedical engineering Mesoporous silica nanoparticles Drug delivery Endogenous and exogenous stimuli Anticancer drug delivery Targeting |
| status_str | publishedVersion |
| title | Recent advances in stimuli-responsive drug release and targeting concepts using mesoporous silica nanoparticles |
| title_full | Recent advances in stimuli-responsive drug release and targeting concepts using mesoporous silica nanoparticles |
| title_fullStr | Recent advances in stimuli-responsive drug release and targeting concepts using mesoporous silica nanoparticles |
| title_full_unstemmed | Recent advances in stimuli-responsive drug release and targeting concepts using mesoporous silica nanoparticles |
| title_short | Recent advances in stimuli-responsive drug release and targeting concepts using mesoporous silica nanoparticles |
| title_sort | Recent advances in stimuli-responsive drug release and targeting concepts using mesoporous silica nanoparticles |
| topic | Biomedical and clinical sciences Pharmacology and pharmaceutical sciences Engineering Biomedical engineering Mesoporous silica nanoparticles Drug delivery Endogenous and exogenous stimuli Anticancer drug delivery Targeting |