Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease

Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease

<p dir="ltr">Several studies reported an association between CSF alpha-synuclein (α-syn) and tau in Alzheimer’s disease (AD), and demonstrated the significance of α-syn in improving the diagnostic sensitivity/specificity of classical AD CSF biomarkers. In the current study, we measur...

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Bibliographic Details
Main Author: Nour K. Majbour (8809316) (author)
Other Authors: Davide Chiasserini (432117) (author), Nishant N. Vaikath (2901785) (author), Paolo Eusebi (432118) (author), Takahiko Tokuda (105837) (author), Wilma van de Berg (3554690) (author), Lucilla Parnetti (120805) (author), Paolo Calabresi (24897) (author), Omar M. A. El-Agnaf (8809331) (author)
Published: 2017
Subjects:
Biomedical and clinical sciences
Neurosciences
Alpha-synuclein (α-syn)
Alzheimer’s disease (AD)
Cerebrospinal fluid (CSF)
Biomarkers
Tau protein
Oligomers
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