Location matters: spatial dynamics of tumor-infiltrating T cell subsets is prognostic in colon cancer

Location matters: spatial dynamics of tumor-infiltrating T cell subsets is prognostic in colon cancer

<h3>Background</h3><p dir="ltr">Colon cancer is a heterogeneous disease and consists of various molecular subtypes. Despite advances in high-throughput expression profiling, limitations remain in predicting clinical outcome and assigning specific treatment to individual c...

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Main Author: Hehuan Zhu (4808445) (author)
Other Authors: Jessica Roelands (7516439) (author), Eiman I. Ahmed (6595514) (author), Imke Stouten (17901620) (author), Rachel Hoorntje (17901623) (author), Ronald L. P. van Vlierberghe (17901626) (author), Marieke E. Ijsselsteijn (7571399) (author), Xin Lei (1622128) (author), Noel F. C. C. de Miranda (7571405) (author), Rob A. E. M. Tollenaar (8115839) (author), Alexander L. Vahrmeijer (8449359) (author), Davide Bedognetti (2632474) (author), Wouter R. L. Hendrickx (17449924) (author), Peter J. K. Kuppen (9858902) (author)
Published: 2024
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Immunology
Oncology and carcinogenesis
colon cancer
multiplex immunofluorescence
T cell
spatial analysis
tumor microenvironment
immunologic constant of rejection
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