Impact of Stapedectomy on Tinnitus Severity and Hearing Outcomes in Patients With Otosclerosis: A Systematic Review
<h3 dir="ltr">Introduction</h3><p dir="ltr">Otosclerosis is a progressive, autosomal dominant hereditary disease of temporal bone causing tinnitus, and conductive hearing loss. Stapes surgery is safe and effective treatment with evidence suggesting tinnitus impr...
محفوظ في:
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| مؤلفون آخرون: | |
| منشور في: |
2025
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إضافة وسم
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| الملخص: | <h3 dir="ltr">Introduction</h3><p dir="ltr">Otosclerosis is a progressive, autosomal dominant hereditary disease of temporal bone causing tinnitus, and conductive hearing loss. Stapes surgery is safe and effective treatment with evidence suggesting tinnitus improvement corelates with hearing restoration. This systematic review evaluates evidence related to tinnitus improvement and hearing restoration following stapedectomy.</p><h3 dir="ltr">Methods</h3><p dir="ltr">This systematic review was prepared in accordance with the Preferred Reporting Item for Systematic Review and Meta-Analysis-P statement. The search included bibliographic databases like MEDLINE, EMBASE, the Cumulative Index of Nursing and Allied Health Literature, and Cochrane Library from inception until June 2024. The review included all studies reporting tinnitus severity and hearing outcomes post-stapes surgery. Outcome measures were tinnitus severity, hearing improvement, and timeframe of improvement. This review was registered with PROSPERO (CRD42024566593).</p><h3 dir="ltr">Result</h3><p dir="ltr">The initial search generated 609 studies from multiple databases, of which 22 studies involving 2233 patients were included. Due to heterogeneity in study design, patient population, and outcome measures used, pooling of data for meta-analysis was not feasible. Most of the studies were prospective in nature (77.3%), conducted in university hospitals (45.5%), and the average mean age of patients ranged from 18 to 75 years, predominantly females (60.7%). Most studies reported improvement of tinnitus severity post-stapes surgery 15.7% to 64% (median 46.3%), only fewer studies noted worsening among 2.9% to 11% patients. Hearing outcomes were consistently positive among majority of the studies, and only a small subset of patients reported no improvement or worsening. There was a moderate-to-strong relation between tinnitus improvement and air-bone gap (ABG) closure (32%), tinnitus resolution versus ABG closure (55%). More than 50% of the studies reported adherence to the Strengthening the Reporting of Observational Studies in Epidemiology quality assessment checklist.</p><h3 dir="ltr">Conclusion</h3><p dir="ltr">The systematic review indicates that stapes surgery improves degree of tinnitus severity and hearing outcomes and has moderate-to-strong correlation between resolution in tinnitus versus ABG closure. Most patients experienced significant improvement within 6 months.</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: Ear, Nose & Throat Journal<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1177/01455613251382671" target="_blank">https://dx.doi.org/10.1177/01455613251382671</a></p> |
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