Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish
<p dir="ltr">Chemicals are at the top of public health concerns and metals have received much attention in terms of toxicological studies. Cadmium (Cd) and mercury (Hg) are among the most toxic heavy metals and are widely distributed in the environment. They are considered important...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | |
| منشور في: |
2023
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| الموضوعات: | |
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إضافة وسم
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| _version_ | 1864513564667019264 |
|---|---|
| author | Azza Naija (15749672) |
| author2 | Huseyin Cagatay Yalcin (15749682) |
| author2_role | author |
| author_facet | Azza Naija (15749672) Huseyin Cagatay Yalcin (15749682) |
| author_role | author |
| dc.creator.none.fl_str_mv | Azza Naija (15749672) Huseyin Cagatay Yalcin (15749682) |
| dc.date.none.fl_str_mv | 2023-01-01T00:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.toxrep.2023.04.009 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Evaluation_of_cadmium_and_mercury_on_cardiovascular_and_neurological_systems_Effects_on_humans_and_fish/23009954 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Cardiovascular medicine and haematology Neurosciences Cadmium Mercury Fish Humans Heart Brain |
| dc.title.none.fl_str_mv | Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Chemicals are at the top of public health concerns and metals have received much attention in terms of toxicological studies. Cadmium (Cd) and mercury (Hg) are among the most toxic heavy metals and are widely distributed in the environment. They are considered important factors involved in several organ disturbances. Heart and brain tissues are not among the first exposure sites to Cd and Hg but they are directly affected and may manifest intoxication reactions leading to death. Many cases of human intoxication with Cd and Hg showed that these metals have potential cardiotoxic and neurotoxic effects. Human exposure to heavy metals is through fish consumption which is considered as an excellent source of human nutrients. In the current review, we will summarize the most known cases of human intoxication with Cd and Hg, highlight their toxic effects on fish, and investigate the common signal pathways of both Cd and Hg to affect heart and brain tissues. Also, we will present the most common biomarkers used in the assessment of cardiotoxicity and neurotoxicity using Zebrafish model.</p><h2>Other Information</h2><p dir="ltr">Published in: Toxicology Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher'swebsite: <a href="http://dx.doi.org/10.1016/j.toxrep.2023.04.009" target="_blank">http://dx.doi.org/10.1016/j.toxrep.2023.04.009</a><a href="http://dx.doi.org/10.1016/elsevier_cm_policy" target="_blank"></a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_3d5f0279f5dff698e8080f5be00620a7 |
| identifier_str_mv | 10.1016/j.toxrep.2023.04.009 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/23009954 |
| publishDate | 2023 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fishAzza Naija (15749672)Huseyin Cagatay Yalcin (15749682)Biomedical and clinical sciencesCardiovascular medicine and haematologyNeurosciencesCadmiumMercuryFishHumansHeartBrain<p dir="ltr">Chemicals are at the top of public health concerns and metals have received much attention in terms of toxicological studies. Cadmium (Cd) and mercury (Hg) are among the most toxic heavy metals and are widely distributed in the environment. They are considered important factors involved in several organ disturbances. Heart and brain tissues are not among the first exposure sites to Cd and Hg but they are directly affected and may manifest intoxication reactions leading to death. Many cases of human intoxication with Cd and Hg showed that these metals have potential cardiotoxic and neurotoxic effects. Human exposure to heavy metals is through fish consumption which is considered as an excellent source of human nutrients. In the current review, we will summarize the most known cases of human intoxication with Cd and Hg, highlight their toxic effects on fish, and investigate the common signal pathways of both Cd and Hg to affect heart and brain tissues. Also, we will present the most common biomarkers used in the assessment of cardiotoxicity and neurotoxicity using Zebrafish model.</p><h2>Other Information</h2><p dir="ltr">Published in: Toxicology Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher'swebsite: <a href="http://dx.doi.org/10.1016/j.toxrep.2023.04.009" target="_blank">http://dx.doi.org/10.1016/j.toxrep.2023.04.009</a><a href="http://dx.doi.org/10.1016/elsevier_cm_policy" target="_blank"></a></p>2023-01-01T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.toxrep.2023.04.009https://figshare.com/articles/journal_contribution/Evaluation_of_cadmium_and_mercury_on_cardiovascular_and_neurological_systems_Effects_on_humans_and_fish/23009954CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/230099542023-01-01T00:00:00Z |
| spellingShingle | Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish Azza Naija (15749672) Biomedical and clinical sciences Cardiovascular medicine and haematology Neurosciences Cadmium Mercury Fish Humans Heart Brain |
| status_str | publishedVersion |
| title | Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish |
| title_full | Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish |
| title_fullStr | Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish |
| title_full_unstemmed | Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish |
| title_short | Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish |
| title_sort | Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish |
| topic | Biomedical and clinical sciences Cardiovascular medicine and haematology Neurosciences Cadmium Mercury Fish Humans Heart Brain |