Mechanical properties of human hepatic tissues to develop liver-mimicking phantoms for medical applications

<div><p>Using liver phantoms for mimicking human tissue in clinical training, disease diagnosis, and treatment planning is a common practice. The fabrication material of the liver phantom should exhibit mechanical properties similar to those of the real liver organ in the human body. Thi...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Aicha S. Lemine (17148352) (author)
مؤلفون آخرون: Zubair Ahmad (4345072) (author), Noora J. Al-Thani (17017695) (author), Anwarul Hasan (1332066) (author), Jolly Bhadra (14147823) (author)
منشور في: 2023
الموضوعات:
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author Aicha S. Lemine (17148352)
author2 Zubair Ahmad (4345072)
Noora J. Al-Thani (17017695)
Anwarul Hasan (1332066)
Jolly Bhadra (14147823)
author2_role author
author
author
author
author_facet Aicha S. Lemine (17148352)
Zubair Ahmad (4345072)
Noora J. Al-Thani (17017695)
Anwarul Hasan (1332066)
Jolly Bhadra (14147823)
author_role author
dc.creator.none.fl_str_mv Aicha S. Lemine (17148352)
Zubair Ahmad (4345072)
Noora J. Al-Thani (17017695)
Anwarul Hasan (1332066)
Jolly Bhadra (14147823)
dc.date.none.fl_str_mv 2023-12-10T03:00:00Z
dc.identifier.none.fl_str_mv 10.1007/s10237-023-01785-4
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Mechanical_properties_of_human_hepatic_tissues_to_develop_liver-mimicking_phantoms_for_medical_applications/24921381
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Clinical sciences
Engineering
Biomedical engineering
Liver
Phantoms
Mechanical properties
Tissue-mimicking
Viscosity
Elasticity
dc.title.none.fl_str_mv Mechanical properties of human hepatic tissues to develop liver-mimicking phantoms for medical applications
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <div><p>Using liver phantoms for mimicking human tissue in clinical training, disease diagnosis, and treatment planning is a common practice. The fabrication material of the liver phantom should exhibit mechanical properties similar to those of the real liver organ in the human body. This tissue-equivalent material is essential for qualitative and quantitative investigation of the liver mechanisms in producing nutrients, excretion of waste metabolites, and tissue deformity at mechanical stimulus. This paper reviews the mechanical properties of human hepatic tissues to develop liver-mimicking phantoms. These properties include viscosity, elasticity, acoustic impedance, sound speed, and attenuation. The advantages and disadvantages of the most common fabrication materials for developing liver tissue-mimicking phantoms are also highlighted. Such phantoms will give a better insight into the real tissue damage during the disease progression and preservation for transplantation. The liver tissue-mimicking phantom will raise the quality assurance of patient diagnostic and treatment precision and offer a definitive clinical trial data collection.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Biomechanics and Modeling in Mechanobiology<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s10237-023-01785-4" target="_blank">https://dx.doi.org/10.1007/s10237-023-01785-4</a></p>
eu_rights_str_mv openAccess
id Manara2_412e7fed6326182acfe26149eccc9bda
identifier_str_mv 10.1007/s10237-023-01785-4
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/24921381
publishDate 2023
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rights_invalid_str_mv CC BY 4.0
spelling Mechanical properties of human hepatic tissues to develop liver-mimicking phantoms for medical applicationsAicha S. Lemine (17148352)Zubair Ahmad (4345072)Noora J. Al-Thani (17017695)Anwarul Hasan (1332066)Jolly Bhadra (14147823)Biomedical and clinical sciencesClinical sciencesEngineeringBiomedical engineeringLiverPhantomsMechanical propertiesTissue-mimickingViscosityElasticity<div><p>Using liver phantoms for mimicking human tissue in clinical training, disease diagnosis, and treatment planning is a common practice. The fabrication material of the liver phantom should exhibit mechanical properties similar to those of the real liver organ in the human body. This tissue-equivalent material is essential for qualitative and quantitative investigation of the liver mechanisms in producing nutrients, excretion of waste metabolites, and tissue deformity at mechanical stimulus. This paper reviews the mechanical properties of human hepatic tissues to develop liver-mimicking phantoms. These properties include viscosity, elasticity, acoustic impedance, sound speed, and attenuation. The advantages and disadvantages of the most common fabrication materials for developing liver tissue-mimicking phantoms are also highlighted. Such phantoms will give a better insight into the real tissue damage during the disease progression and preservation for transplantation. The liver tissue-mimicking phantom will raise the quality assurance of patient diagnostic and treatment precision and offer a definitive clinical trial data collection.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Biomechanics and Modeling in Mechanobiology<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s10237-023-01785-4" target="_blank">https://dx.doi.org/10.1007/s10237-023-01785-4</a></p>2023-12-10T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s10237-023-01785-4https://figshare.com/articles/journal_contribution/Mechanical_properties_of_human_hepatic_tissues_to_develop_liver-mimicking_phantoms_for_medical_applications/24921381CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/249213812023-12-10T03:00:00Z
spellingShingle Mechanical properties of human hepatic tissues to develop liver-mimicking phantoms for medical applications
Aicha S. Lemine (17148352)
Biomedical and clinical sciences
Clinical sciences
Engineering
Biomedical engineering
Liver
Phantoms
Mechanical properties
Tissue-mimicking
Viscosity
Elasticity
status_str publishedVersion
title Mechanical properties of human hepatic tissues to develop liver-mimicking phantoms for medical applications
title_full Mechanical properties of human hepatic tissues to develop liver-mimicking phantoms for medical applications
title_fullStr Mechanical properties of human hepatic tissues to develop liver-mimicking phantoms for medical applications
title_full_unstemmed Mechanical properties of human hepatic tissues to develop liver-mimicking phantoms for medical applications
title_short Mechanical properties of human hepatic tissues to develop liver-mimicking phantoms for medical applications
title_sort Mechanical properties of human hepatic tissues to develop liver-mimicking phantoms for medical applications
topic Biomedical and clinical sciences
Clinical sciences
Engineering
Biomedical engineering
Liver
Phantoms
Mechanical properties
Tissue-mimicking
Viscosity
Elasticity