Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model

<div><p>Variants in cardiac myosin-binding protein C (cMyBP-C) are the leading cause of inherited hypertrophic cardiomyopathy (HCM), demonstrating the key role that cMyBP-C plays in the heart’s contractile machinery. To investigate the c-MYBPC3 HCM-related cardiac impairment, we generate...

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المؤلف الرئيسي:	Sahar Isa Da’as (18288880) (author)
مؤلفون آخرون:	Waseem Hasan (17280670) (author), Rola Salem (18288883) (author), Nadine Younes (14779150) (author), Doua Abdelrahman (17280667) (author), Iman A. Mohamed (18288886) (author), Arwa Aldaalis (13355328) (author), Ramzi Temanni (671528) (author), Lisa Sara Mathew (17886698) (author), Stephan Lorenz (466378) (author), Magdi Yacoub (6893000) (author), Michail Nomikos (17563188) (author), Gheyath K. Nasrallah (9200525) (author), Khalid A. Fakhro (3158862) (author)
منشور في:	2022
الموضوعات:	Biological sciences Zoology Chemical sciences Inorganic chemistry Organic chemistry Physical chemistry Theoretical and computational chemistry hypertrophic cardiomyopathy HCM c-MYBPC3 actin RNA seq zebrafish knockout
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Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model

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