Saddle pulmonary embolism in the setting of COVID-19 infection: A systematic review of case reports and case series
<div><p>Saddle pulmonary embolism (SPE) is a rare type of pulmonary embolism that can lead to hemodynamic compromise causing sudden deaths. Due to a dearth of large prospective studies in this area, little is known regarding the epidemiology, and prognosis and factors affecting the latte...
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| مؤلفون آخرون: | , , , , , , |
| منشور في: |
2023
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| _version_ | 1864513526514581504 |
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| author | Hassan Choudry (12217767) |
| author2 | Fateen Ata (12217764) Wanis Ibrahim (14777290) Mohammad Omer Rehman Rana (18021619) Shoaib Ahmad (10035424) Asim Mehmood (5694785) Basir Afzaal Gill (18021622) Mahammed Khan Suheb (18021625) |
| author2_role | author author author author author author author |
| author_facet | Hassan Choudry (12217767) Fateen Ata (12217764) Wanis Ibrahim (14777290) Mohammad Omer Rehman Rana (18021619) Shoaib Ahmad (10035424) Asim Mehmood (5694785) Basir Afzaal Gill (18021622) Mahammed Khan Suheb (18021625) |
| author_role | author |
| dc.creator.none.fl_str_mv | Hassan Choudry (12217767) Fateen Ata (12217764) Wanis Ibrahim (14777290) Mohammad Omer Rehman Rana (18021619) Shoaib Ahmad (10035424) Asim Mehmood (5694785) Basir Afzaal Gill (18021622) Mahammed Khan Suheb (18021625) |
| dc.date.none.fl_str_mv | 2023-06-01T00:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1515/med-2023-0724 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Saddle_pulmonary_embolism_in_the_setting_of_COVID-19_infection_A_systematic_review_of_case_reports_and_case_series/25284952 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Cardiovascular medicine and haematology saddle pulmonary embolism COVID-19 SARS-CoV-2 |
| dc.title.none.fl_str_mv | Saddle pulmonary embolism in the setting of COVID-19 infection: A systematic review of case reports and case series |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <div><p>Saddle pulmonary embolism (SPE) is a rare type of pulmonary embolism that can lead to hemodynamic compromise causing sudden deaths. Due to a dearth of large prospective studies in this area, little is known regarding the epidemiology, and prognosis and factors affecting the latter for COVID-19-associated SPE. We aimed to describe COVID-19-associated SPE and quantify and compare mortality and factors affecting mortality among the cases. We included a total of 25 publications with a total of 35 cases. The average age was 45 ± 16.3 years with 11 females and 24 males. Dyspnoea (82.5%), orthopnoea (43.5%), and cough (43.5%) were the most common symptoms, and obstructive shock was present in five (21.7%) patients. The average reported oxygen (O2) saturation was 85.8% ± 11.9 mm Hg. Hypertension (26.1%), diabetes (21.7%), and deep vein thrombosis (21.7%) were the most commonly reported comorbidities. Right heart strain was recognized in seven (30%) patients on electroencephalogram (S1QIIITIII) and 12 (52.2%) patients on echocardiogram. Anticoagulation, thrombolysis, and percutaneous intervention were tried in 21 (91.3%), 13 (56.5%), and 6 (26.1%) cases, respectively. Despite the aggressive management, 2 of 25 (8.7%) patients died in our smaller case report cohort. We conclude that despite aggressive management modalities, the mortality of SPE remains high in COVID-19.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Open Medicine<br> License: <a href="http://creativecommons.org/licenses/by/4.0" target="_blank">http://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1515/med-2023-0724" target="_blank">https://dx.doi.org/10.1515/med-2023-0724</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_4731bb579c4d82ce6e1eddd5a217de77 |
| identifier_str_mv | 10.1515/med-2023-0724 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/25284952 |
| publishDate | 2023 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Saddle pulmonary embolism in the setting of COVID-19 infection: A systematic review of case reports and case seriesHassan Choudry (12217767)Fateen Ata (12217764)Wanis Ibrahim (14777290)Mohammad Omer Rehman Rana (18021619)Shoaib Ahmad (10035424)Asim Mehmood (5694785)Basir Afzaal Gill (18021622)Mahammed Khan Suheb (18021625)Biomedical and clinical sciencesCardiovascular medicine and haematologysaddle pulmonary embolismCOVID-19SARS-CoV-2<div><p>Saddle pulmonary embolism (SPE) is a rare type of pulmonary embolism that can lead to hemodynamic compromise causing sudden deaths. Due to a dearth of large prospective studies in this area, little is known regarding the epidemiology, and prognosis and factors affecting the latter for COVID-19-associated SPE. We aimed to describe COVID-19-associated SPE and quantify and compare mortality and factors affecting mortality among the cases. We included a total of 25 publications with a total of 35 cases. The average age was 45 ± 16.3 years with 11 females and 24 males. Dyspnoea (82.5%), orthopnoea (43.5%), and cough (43.5%) were the most common symptoms, and obstructive shock was present in five (21.7%) patients. The average reported oxygen (O2) saturation was 85.8% ± 11.9 mm Hg. Hypertension (26.1%), diabetes (21.7%), and deep vein thrombosis (21.7%) were the most commonly reported comorbidities. Right heart strain was recognized in seven (30%) patients on electroencephalogram (S1QIIITIII) and 12 (52.2%) patients on echocardiogram. Anticoagulation, thrombolysis, and percutaneous intervention were tried in 21 (91.3%), 13 (56.5%), and 6 (26.1%) cases, respectively. Despite the aggressive management, 2 of 25 (8.7%) patients died in our smaller case report cohort. We conclude that despite aggressive management modalities, the mortality of SPE remains high in COVID-19.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Open Medicine<br> License: <a href="http://creativecommons.org/licenses/by/4.0" target="_blank">http://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1515/med-2023-0724" target="_blank">https://dx.doi.org/10.1515/med-2023-0724</a></p>2023-06-01T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1515/med-2023-0724https://figshare.com/articles/journal_contribution/Saddle_pulmonary_embolism_in_the_setting_of_COVID-19_infection_A_systematic_review_of_case_reports_and_case_series/25284952CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/252849522023-06-01T00:00:00Z |
| spellingShingle | Saddle pulmonary embolism in the setting of COVID-19 infection: A systematic review of case reports and case series Hassan Choudry (12217767) Biomedical and clinical sciences Cardiovascular medicine and haematology saddle pulmonary embolism COVID-19 SARS-CoV-2 |
| status_str | publishedVersion |
| title | Saddle pulmonary embolism in the setting of COVID-19 infection: A systematic review of case reports and case series |
| title_full | Saddle pulmonary embolism in the setting of COVID-19 infection: A systematic review of case reports and case series |
| title_fullStr | Saddle pulmonary embolism in the setting of COVID-19 infection: A systematic review of case reports and case series |
| title_full_unstemmed | Saddle pulmonary embolism in the setting of COVID-19 infection: A systematic review of case reports and case series |
| title_short | Saddle pulmonary embolism in the setting of COVID-19 infection: A systematic review of case reports and case series |
| title_sort | Saddle pulmonary embolism in the setting of COVID-19 infection: A systematic review of case reports and case series |
| topic | Biomedical and clinical sciences Cardiovascular medicine and haematology saddle pulmonary embolism COVID-19 SARS-CoV-2 |