Pegcetacoplan ‐ a novel C3 inhibitor for paroxysmal nocturnal hemoglobinuria

Pegcetacoplan ‐ a novel C3 inhibitor for paroxysmal nocturnal hemoglobinuria

<p dir="ltr">Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, chronic, life-threatening hematologic disorder due to clonal expansion of mutated bone marrow stem cells, in which their progeny lose the capacity to bind proteins to the cell surface. Chronic and/or paroxysmal intrava...

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Bibliographic Details
Main Author: Syeda Tayyaba Rehan (16897080) (author)
Other Authors: Mahnoor Rehan Hashmi (17122952) (author), Muhammad Sohaib Asghar (10395401) (author), Muhammad Junaid Tahir (11654666) (author), Zohaib Yousaf (9617058) (author)
Published: 2022
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Pharmacology and pharmaceutical sciences
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Hematologic Disorder
Complement Inhibitors
CD55 and CD59
Intravascular Hemolysis
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