Extremity Ischemia After Jellyfish Envenomation: A Case Report and Systematic Review of the Literature
<h3>Background</h3><p dir="ltr">Extremity ischemia and necrosis after jellyfish envenomation can be mutilating and cause long-term functional deficits. The best way to manage these presentations is unknown.</p><h3>Objective</h3><p dir="ltr"&...
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2022
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| _version_ | 1864513536473956352 |
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| author | Saif Badran (16888785) |
| author2 | Yazeed Eldos (17545749) Robert J. Hoffman (17545752) Sabeena Obaray (17545755) Bran Sivakumar (6819863) Graeme E. Glass (17545758) |
| author2_role | author author author author author |
| author_facet | Saif Badran (16888785) Yazeed Eldos (17545749) Robert J. Hoffman (17545752) Sabeena Obaray (17545755) Bran Sivakumar (6819863) Graeme E. Glass (17545758) |
| author_role | author |
| dc.creator.none.fl_str_mv | Saif Badran (16888785) Yazeed Eldos (17545749) Robert J. Hoffman (17545752) Sabeena Obaray (17545755) Bran Sivakumar (6819863) Graeme E. Glass (17545758) |
| dc.date.none.fl_str_mv | 2022-10-01T00:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.jemermed.2022.06.014 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Extremity_Ischemia_After_Jellyfish_Envenomation_A_Case_Report_and_Systematic_Review_of_the_Literature/24720444 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Ischemia Envenomation Prostaglandin Thrombolytic |
| dc.title.none.fl_str_mv | Extremity Ischemia After Jellyfish Envenomation: A Case Report and Systematic Review of the Literature |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Background</h3><p dir="ltr">Extremity ischemia and necrosis after jellyfish envenomation can be mutilating and cause long-term functional deficits. The best way to manage these presentations is unknown.</p><h3>Objective</h3><p dir="ltr">The aim of this review was to establish an evidence-based consensus for the management of extremity ischemia after jellyfish envenomation.</p><h3>Methods</h3><p dir="ltr">A systematic review of cases of extremity ischemia and necrosis after envenomation by marine cnidarians was performed to clarify what is and what is not known about management and outcomes, to draw conclusions about how best to manage these rare presentations, and to establish an evidence-based algorithm.</p><h3>Results</h3><p dir="ltr">The ischemic sequelae of envenomation typically evolves over a few days. Close medical supervision is necessary to react promptly to the evolving clinical scenario. In the literature, 15 different pharmacologic classes have been used to manage these presentations. Only IV infusions of prostaglandin derivatives and intra-arterial thrombolytics have been found to improve the clinical picture and avoid the need for surgical fasciotomy and debridement in some cases. Anticoagulants, antiplatelet agents, steroids, antibiotics, and nitrates, which are among the most commonly prescribed pharmacologic agents, have not been observed to alter the clinical picture.</p><h3>Conclusions</h3><p dir="ltr">Surgery for compartment syndrome and necrosis are common sequelae of extremity envenomation by marine cnidarians. Only prompt use of IV prostaglandins or intra-arterial thrombolytics can halt ischemic progression and avoid the need for surgery. An algorithm is proposed to guide management of these rare and mutilative presentations.</p><h2>Other Information</h2><p dir="ltr">Published in: The Journal of Emergency Medicine<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jemermed.2022.06.014" target="_blank">https://dx.doi.org/10.1016/j.jemermed.2022.06.014</a></p><p dir="ltr">Additional institutions affiliated with: Qatar Poison Center - Sidra Medicine</p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_4a530b66893e7e1bcf16eb7df112b675 |
| identifier_str_mv | 10.1016/j.jemermed.2022.06.014 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/24720444 |
| publishDate | 2022 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Extremity Ischemia After Jellyfish Envenomation: A Case Report and Systematic Review of the LiteratureSaif Badran (16888785)Yazeed Eldos (17545749)Robert J. Hoffman (17545752)Sabeena Obaray (17545755)Bran Sivakumar (6819863)Graeme E. Glass (17545758)Biomedical and clinical sciencesClinical sciencesIschemiaEnvenomationProstaglandinThrombolytic<h3>Background</h3><p dir="ltr">Extremity ischemia and necrosis after jellyfish envenomation can be mutilating and cause long-term functional deficits. The best way to manage these presentations is unknown.</p><h3>Objective</h3><p dir="ltr">The aim of this review was to establish an evidence-based consensus for the management of extremity ischemia after jellyfish envenomation.</p><h3>Methods</h3><p dir="ltr">A systematic review of cases of extremity ischemia and necrosis after envenomation by marine cnidarians was performed to clarify what is and what is not known about management and outcomes, to draw conclusions about how best to manage these rare presentations, and to establish an evidence-based algorithm.</p><h3>Results</h3><p dir="ltr">The ischemic sequelae of envenomation typically evolves over a few days. Close medical supervision is necessary to react promptly to the evolving clinical scenario. In the literature, 15 different pharmacologic classes have been used to manage these presentations. Only IV infusions of prostaglandin derivatives and intra-arterial thrombolytics have been found to improve the clinical picture and avoid the need for surgical fasciotomy and debridement in some cases. Anticoagulants, antiplatelet agents, steroids, antibiotics, and nitrates, which are among the most commonly prescribed pharmacologic agents, have not been observed to alter the clinical picture.</p><h3>Conclusions</h3><p dir="ltr">Surgery for compartment syndrome and necrosis are common sequelae of extremity envenomation by marine cnidarians. Only prompt use of IV prostaglandins or intra-arterial thrombolytics can halt ischemic progression and avoid the need for surgery. An algorithm is proposed to guide management of these rare and mutilative presentations.</p><h2>Other Information</h2><p dir="ltr">Published in: The Journal of Emergency Medicine<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jemermed.2022.06.014" target="_blank">https://dx.doi.org/10.1016/j.jemermed.2022.06.014</a></p><p dir="ltr">Additional institutions affiliated with: Qatar Poison Center - Sidra Medicine</p>2022-10-01T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.jemermed.2022.06.014https://figshare.com/articles/journal_contribution/Extremity_Ischemia_After_Jellyfish_Envenomation_A_Case_Report_and_Systematic_Review_of_the_Literature/24720444CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/247204442022-10-01T00:00:00Z |
| spellingShingle | Extremity Ischemia After Jellyfish Envenomation: A Case Report and Systematic Review of the Literature Saif Badran (16888785) Biomedical and clinical sciences Clinical sciences Ischemia Envenomation Prostaglandin Thrombolytic |
| status_str | publishedVersion |
| title | Extremity Ischemia After Jellyfish Envenomation: A Case Report and Systematic Review of the Literature |
| title_full | Extremity Ischemia After Jellyfish Envenomation: A Case Report and Systematic Review of the Literature |
| title_fullStr | Extremity Ischemia After Jellyfish Envenomation: A Case Report and Systematic Review of the Literature |
| title_full_unstemmed | Extremity Ischemia After Jellyfish Envenomation: A Case Report and Systematic Review of the Literature |
| title_short | Extremity Ischemia After Jellyfish Envenomation: A Case Report and Systematic Review of the Literature |
| title_sort | Extremity Ischemia After Jellyfish Envenomation: A Case Report and Systematic Review of the Literature |
| topic | Biomedical and clinical sciences Clinical sciences Ischemia Envenomation Prostaglandin Thrombolytic |