A case of crescentic glomerulonephritis in a patient with COVID-19 infection
<h3>Rationale:</h3><p dir="ltr">Kidney involvement with COVID-19 infection is a well-known complication, and the majority of kidney involvement is related to ischemic injury/acute tubular injury. However, there are some cases of glomerulonephritis, the etiology of which i...
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2022
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| Summary: | <h3>Rationale:</h3><p dir="ltr">Kidney involvement with COVID-19 infection is a well-known complication, and the majority of kidney involvement is related to ischemic injury/acute tubular injury. However, there are some cases of glomerulonephritis, the etiology of which is not yet known, but an immune process is likely to be the trigger.</p><h3>Patient concerns:</h3><p dir="ltr">A 27-year-old man presented to our hospital with facial puffiness and lower-limb swelling.</p><h3>Diagnosis:</h3><p dir="ltr">Laboratory assessment revealed features of impaired kidney function with proteinuria and hematuria; COVID-19 polymerase chain reaction was positive, which was consistent with pauci-immune crescentic focal segmental glomerulonephritis.</p><h3>Intervention:</h3><p dir="ltr">After renal biopsy, the patient was started on methylprednisolone and rituximab. Due to worsening kidney parameters, he underwent intermittent hemodialysis as needed.</p><h3>Outcome:</h3><p dir="ltr">Kidney function tests partially improved; he was discharged on oral steroids with follow-up in the nephrology clinic to observe for the need for further hemodialysis.</p><h3>Lessons:</h3><p dir="ltr">We conducted a literature review of cases of glomerulonephritis associated with COVID-19 and described numerous types of glomerulonephritis. This report highlights the importance of recognizing emerging glomerulonephritis with COVID-19, the different pathological patterns of renal biopsies, and management interventions and responses.</p><h2>Other Information</h2><p dir="ltr">Published in: Medicine<br>License: <a href="http://creativecommons.org/licenses/by/4.0" target="_blank">http://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1097/md.0000000000028754" target="_blank">https://dx.doi.org/10.1097/md.0000000000028754</a></p> |
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