A case of crescentic glomerulonephritis in a patient with COVID-19 infection
<h3>Rationale:</h3><p dir="ltr">Kidney involvement with COVID-19 infection is a well-known complication, and the majority of kidney involvement is related to ischemic injury/acute tubular injury. However, there are some cases of glomerulonephritis, the etiology of which i...
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2022
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| _version_ | 1864513519872901120 |
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| author | Mouhammad J. Alawad (14777965) |
| author2 | Eihab A. Subahi (12217761) Haneen A. Al-Ani (17191618) Noheir M. Taha (17128771) Ijaz Kamal (9376844) |
| author2_role | author author author author |
| author_facet | Mouhammad J. Alawad (14777965) Eihab A. Subahi (12217761) Haneen A. Al-Ani (17191618) Noheir M. Taha (17128771) Ijaz Kamal (9376844) |
| author_role | author |
| dc.creator.none.fl_str_mv | Mouhammad J. Alawad (14777965) Eihab A. Subahi (12217761) Haneen A. Al-Ani (17191618) Noheir M. Taha (17128771) Ijaz Kamal (9376844) |
| dc.date.none.fl_str_mv | 2022-02-18T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1097/md.0000000000028754 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/A_case_of_crescentic_glomerulonephritis_in_a_patient_with_COVID-19_infection/25441765 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Cardiovascular medicine and haematology acute kidney injury (AKI) antineutrophilic cytoplasmic antibodies (ANCA) COVID-19 infection focal segmental glomerulosclerosis (FSGS) glomerulonephritis (GN) |
| dc.title.none.fl_str_mv | A case of crescentic glomerulonephritis in a patient with COVID-19 infection |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Rationale:</h3><p dir="ltr">Kidney involvement with COVID-19 infection is a well-known complication, and the majority of kidney involvement is related to ischemic injury/acute tubular injury. However, there are some cases of glomerulonephritis, the etiology of which is not yet known, but an immune process is likely to be the trigger.</p><h3>Patient concerns:</h3><p dir="ltr">A 27-year-old man presented to our hospital with facial puffiness and lower-limb swelling.</p><h3>Diagnosis:</h3><p dir="ltr">Laboratory assessment revealed features of impaired kidney function with proteinuria and hematuria; COVID-19 polymerase chain reaction was positive, which was consistent with pauci-immune crescentic focal segmental glomerulonephritis.</p><h3>Intervention:</h3><p dir="ltr">After renal biopsy, the patient was started on methylprednisolone and rituximab. Due to worsening kidney parameters, he underwent intermittent hemodialysis as needed.</p><h3>Outcome:</h3><p dir="ltr">Kidney function tests partially improved; he was discharged on oral steroids with follow-up in the nephrology clinic to observe for the need for further hemodialysis.</p><h3>Lessons:</h3><p dir="ltr">We conducted a literature review of cases of glomerulonephritis associated with COVID-19 and described numerous types of glomerulonephritis. This report highlights the importance of recognizing emerging glomerulonephritis with COVID-19, the different pathological patterns of renal biopsies, and management interventions and responses.</p><h2>Other Information</h2><p dir="ltr">Published in: Medicine<br>License: <a href="http://creativecommons.org/licenses/by/4.0" target="_blank">http://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1097/md.0000000000028754" target="_blank">https://dx.doi.org/10.1097/md.0000000000028754</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_4b4e234c75b4074329cea4a8ae4a399b |
| identifier_str_mv | 10.1097/md.0000000000028754 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/25441765 |
| publishDate | 2022 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | A case of crescentic glomerulonephritis in a patient with COVID-19 infectionMouhammad J. Alawad (14777965)Eihab A. Subahi (12217761)Haneen A. Al-Ani (17191618)Noheir M. Taha (17128771)Ijaz Kamal (9376844)Biomedical and clinical sciencesCardiovascular medicine and haematologyacute kidney injury (AKI)antineutrophilic cytoplasmic antibodies (ANCA)COVID-19 infectionfocal segmental glomerulosclerosis (FSGS)glomerulonephritis (GN)<h3>Rationale:</h3><p dir="ltr">Kidney involvement with COVID-19 infection is a well-known complication, and the majority of kidney involvement is related to ischemic injury/acute tubular injury. However, there are some cases of glomerulonephritis, the etiology of which is not yet known, but an immune process is likely to be the trigger.</p><h3>Patient concerns:</h3><p dir="ltr">A 27-year-old man presented to our hospital with facial puffiness and lower-limb swelling.</p><h3>Diagnosis:</h3><p dir="ltr">Laboratory assessment revealed features of impaired kidney function with proteinuria and hematuria; COVID-19 polymerase chain reaction was positive, which was consistent with pauci-immune crescentic focal segmental glomerulonephritis.</p><h3>Intervention:</h3><p dir="ltr">After renal biopsy, the patient was started on methylprednisolone and rituximab. Due to worsening kidney parameters, he underwent intermittent hemodialysis as needed.</p><h3>Outcome:</h3><p dir="ltr">Kidney function tests partially improved; he was discharged on oral steroids with follow-up in the nephrology clinic to observe for the need for further hemodialysis.</p><h3>Lessons:</h3><p dir="ltr">We conducted a literature review of cases of glomerulonephritis associated with COVID-19 and described numerous types of glomerulonephritis. This report highlights the importance of recognizing emerging glomerulonephritis with COVID-19, the different pathological patterns of renal biopsies, and management interventions and responses.</p><h2>Other Information</h2><p dir="ltr">Published in: Medicine<br>License: <a href="http://creativecommons.org/licenses/by/4.0" target="_blank">http://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1097/md.0000000000028754" target="_blank">https://dx.doi.org/10.1097/md.0000000000028754</a></p>2022-02-18T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1097/md.0000000000028754https://figshare.com/articles/journal_contribution/A_case_of_crescentic_glomerulonephritis_in_a_patient_with_COVID-19_infection/25441765CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/254417652022-02-18T03:00:00Z |
| spellingShingle | A case of crescentic glomerulonephritis in a patient with COVID-19 infection Mouhammad J. Alawad (14777965) Biomedical and clinical sciences Cardiovascular medicine and haematology acute kidney injury (AKI) antineutrophilic cytoplasmic antibodies (ANCA) COVID-19 infection focal segmental glomerulosclerosis (FSGS) glomerulonephritis (GN) |
| status_str | publishedVersion |
| title | A case of crescentic glomerulonephritis in a patient with COVID-19 infection |
| title_full | A case of crescentic glomerulonephritis in a patient with COVID-19 infection |
| title_fullStr | A case of crescentic glomerulonephritis in a patient with COVID-19 infection |
| title_full_unstemmed | A case of crescentic glomerulonephritis in a patient with COVID-19 infection |
| title_short | A case of crescentic glomerulonephritis in a patient with COVID-19 infection |
| title_sort | A case of crescentic glomerulonephritis in a patient with COVID-19 infection |
| topic | Biomedical and clinical sciences Cardiovascular medicine and haematology acute kidney injury (AKI) antineutrophilic cytoplasmic antibodies (ANCA) COVID-19 infection focal segmental glomerulosclerosis (FSGS) glomerulonephritis (GN) |