An End-to-End Concatenated CNN Attention Model for the Classification of Lung Cancer With XAI Techniques

<p dir="ltr">In the field of medical imaging, deep learning (DL) techniques have made significant contributions to the detection and classification of various cancers. Identifying the precise regions in medical images containing cancerous cells plays a crucial role in the diagnostic...

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Main Author: Fariha Haque (21485518) (author)
Other Authors: Mohammad Asif Hasan (22303759) (author), Md. Abu Ismail Siddique (22503755) (author), Tonmoy Roy (21485527) (author), Tonmoy Kanti Shaha (22503758) (author), Yamina Islam (22303756) (author), Avijit Paul (22303753) (author), Muhammad E. H. Chowdhury (14150526) (author)
Published: 2025
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author Fariha Haque (21485518)
author2 Mohammad Asif Hasan (22303759)
Md. Abu Ismail Siddique (22503755)
Tonmoy Roy (21485527)
Tonmoy Kanti Shaha (22503758)
Yamina Islam (22303756)
Avijit Paul (22303753)
Muhammad E. H. Chowdhury (14150526)
author2_role author
author
author
author
author
author
author
author_facet Fariha Haque (21485518)
Mohammad Asif Hasan (22303759)
Md. Abu Ismail Siddique (22503755)
Tonmoy Roy (21485527)
Tonmoy Kanti Shaha (22503758)
Yamina Islam (22303756)
Avijit Paul (22303753)
Muhammad E. H. Chowdhury (14150526)
author_role author
dc.creator.none.fl_str_mv Fariha Haque (21485518)
Mohammad Asif Hasan (22303759)
Md. Abu Ismail Siddique (22503755)
Tonmoy Roy (21485527)
Tonmoy Kanti Shaha (22503758)
Yamina Islam (22303756)
Avijit Paul (22303753)
Muhammad E. H. Chowdhury (14150526)
dc.date.none.fl_str_mv 2025-06-09T06:00:00Z
dc.identifier.none.fl_str_mv 10.1109/access.2025.3572423
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/An_End-to-End_Concatenated_CNN_Attention_Model_for_the_Classification_of_Lung_Cancer_With_XAI_Techniques/30455570
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Oncology and carcinogenesis
Health sciences
Health services and systems
Information and computing sciences
Artificial intelligence
Lung cancer
convolutional neural network
CLAHE
explainable AI
Shapley additive explanation
gradient-weighted class activation mapping
Gradio
Accuracy
Computed tomography
Feature extraction
Tumors
Transfer learning
Medical diagnostic imaging
Convolutional neural networks
dc.title.none.fl_str_mv An End-to-End Concatenated CNN Attention Model for the Classification of Lung Cancer With XAI Techniques
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">In the field of medical imaging, deep learning (DL) techniques have made significant contributions to the detection and classification of various cancers. Identifying the precise regions in medical images containing cancerous cells plays a crucial role in the diagnostic process. Early and accurate cancer detection is essential for effective treatment and improved patient outcomes. However, manual diagnosis is labor-intensive, requiring the specialized expertise of radiologists, and the increasing number of cancer cases presents challenges in processing large volumes of image data efficiently. To address these challenges, an end-to-end concatenated Convolutional Neural Network (CNN) attention model has been proposed for automatic lung cancer classification. This approach integrates two distinct CNNs, followed by a multi-layer perceptron (MLP) and a multi-head attention (MHA) mechanism, to enhance performance. The model leverages explainable AI techniques, such as gradient-weighted class activation mapping (grad-CAM) and Shapley additive explanations (SHAP), to highlight critical regions within the images that influence the decision-making process. This model achieves impressive performance, with an accuracy of 99.54%, precision of 99.31%, recall of 99.95%, F1-score of 99.66%, and an AUC of 99.97%. These results demonstrate that this approach not only surpasses existing methods but also provides a highly accurate and interpretable solution. By reducing the need for extensive manual intervention, this model enables faster and more reliable lung cancer diagnosis, paving the way for timely and effective treatments.</p><h2>Other Information</h2><p dir="ltr">Published in: IEEE Access<br>License: <a href="https://creativecommons.org/licenses/by/4.0/deed.en" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1109/access.2025.3572423" target="_blank">https://dx.doi.org/10.1109/access.2025.3572423</a></p>
eu_rights_str_mv openAccess
id Manara2_4da2b150ad47d5deb0e37b48bae500e7
identifier_str_mv 10.1109/access.2025.3572423
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/30455570
publishDate 2025
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rights_invalid_str_mv CC BY 4.0
spelling An End-to-End Concatenated CNN Attention Model for the Classification of Lung Cancer With XAI TechniquesFariha Haque (21485518)Mohammad Asif Hasan (22303759)Md. Abu Ismail Siddique (22503755)Tonmoy Roy (21485527)Tonmoy Kanti Shaha (22503758)Yamina Islam (22303756)Avijit Paul (22303753)Muhammad E. H. Chowdhury (14150526)Biomedical and clinical sciencesOncology and carcinogenesisHealth sciencesHealth services and systemsInformation and computing sciencesArtificial intelligenceLung cancerconvolutional neural networkCLAHEexplainable AIShapley additive explanationgradient-weighted class activation mappingGradioAccuracyComputed tomographyFeature extractionTumorsTransfer learningMedical diagnostic imagingConvolutional neural networks<p dir="ltr">In the field of medical imaging, deep learning (DL) techniques have made significant contributions to the detection and classification of various cancers. Identifying the precise regions in medical images containing cancerous cells plays a crucial role in the diagnostic process. Early and accurate cancer detection is essential for effective treatment and improved patient outcomes. However, manual diagnosis is labor-intensive, requiring the specialized expertise of radiologists, and the increasing number of cancer cases presents challenges in processing large volumes of image data efficiently. To address these challenges, an end-to-end concatenated Convolutional Neural Network (CNN) attention model has been proposed for automatic lung cancer classification. This approach integrates two distinct CNNs, followed by a multi-layer perceptron (MLP) and a multi-head attention (MHA) mechanism, to enhance performance. The model leverages explainable AI techniques, such as gradient-weighted class activation mapping (grad-CAM) and Shapley additive explanations (SHAP), to highlight critical regions within the images that influence the decision-making process. This model achieves impressive performance, with an accuracy of 99.54%, precision of 99.31%, recall of 99.95%, F1-score of 99.66%, and an AUC of 99.97%. These results demonstrate that this approach not only surpasses existing methods but also provides a highly accurate and interpretable solution. By reducing the need for extensive manual intervention, this model enables faster and more reliable lung cancer diagnosis, paving the way for timely and effective treatments.</p><h2>Other Information</h2><p dir="ltr">Published in: IEEE Access<br>License: <a href="https://creativecommons.org/licenses/by/4.0/deed.en" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1109/access.2025.3572423" target="_blank">https://dx.doi.org/10.1109/access.2025.3572423</a></p>2025-06-09T06:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1109/access.2025.3572423https://figshare.com/articles/journal_contribution/An_End-to-End_Concatenated_CNN_Attention_Model_for_the_Classification_of_Lung_Cancer_With_XAI_Techniques/30455570CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/304555702025-06-09T06:00:00Z
spellingShingle An End-to-End Concatenated CNN Attention Model for the Classification of Lung Cancer With XAI Techniques
Fariha Haque (21485518)
Biomedical and clinical sciences
Oncology and carcinogenesis
Health sciences
Health services and systems
Information and computing sciences
Artificial intelligence
Lung cancer
convolutional neural network
CLAHE
explainable AI
Shapley additive explanation
gradient-weighted class activation mapping
Gradio
Accuracy
Computed tomography
Feature extraction
Tumors
Transfer learning
Medical diagnostic imaging
Convolutional neural networks
status_str publishedVersion
title An End-to-End Concatenated CNN Attention Model for the Classification of Lung Cancer With XAI Techniques
title_full An End-to-End Concatenated CNN Attention Model for the Classification of Lung Cancer With XAI Techniques
title_fullStr An End-to-End Concatenated CNN Attention Model for the Classification of Lung Cancer With XAI Techniques
title_full_unstemmed An End-to-End Concatenated CNN Attention Model for the Classification of Lung Cancer With XAI Techniques
title_short An End-to-End Concatenated CNN Attention Model for the Classification of Lung Cancer With XAI Techniques
title_sort An End-to-End Concatenated CNN Attention Model for the Classification of Lung Cancer With XAI Techniques
topic Biomedical and clinical sciences
Oncology and carcinogenesis
Health sciences
Health services and systems
Information and computing sciences
Artificial intelligence
Lung cancer
convolutional neural network
CLAHE
explainable AI
Shapley additive explanation
gradient-weighted class activation mapping
Gradio
Accuracy
Computed tomography
Feature extraction
Tumors
Transfer learning
Medical diagnostic imaging
Convolutional neural networks