Post‐COVID‐19‐associated multiorgan complications or “long COVID” with literature review and management strategy discussion: A meta‐analysis
<h3>Objective</h3><p dir="ltr">To investigate the post‐COVID‐19 long‐term complications or long COVID of various organ systems in patients after 3 months of the infection, specifically before the Omicron variant, with comparative literature analysis.</p><h3>Me...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , , , , , , |
| منشور في: |
2023
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| الموضوعات: | |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
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| _version_ | 1864513547848908800 |
|---|---|
| author | Phool Iqbal (12217770) |
| author2 | Fateen Ata (12217764) Hassan Chaudhry (8666385) Bassam Muthanna (14777407) Hafiz Waqas Younas (21385562) Syed Ata ul Munamm (21385565) Rohit Sharma (286462) Kahtan Fadah (21385568) Shereen Elazzazy (9545774) Anas Hamad (9545771) Osama Said Abu Tabar (21385571) Nabil E. Omar (9545756) |
| author2_role | author author author author author author author author author author author |
| author_facet | Phool Iqbal (12217770) Fateen Ata (12217764) Hassan Chaudhry (8666385) Bassam Muthanna (14777407) Hafiz Waqas Younas (21385562) Syed Ata ul Munamm (21385565) Rohit Sharma (286462) Kahtan Fadah (21385568) Shereen Elazzazy (9545774) Anas Hamad (9545771) Osama Said Abu Tabar (21385571) Nabil E. Omar (9545756) |
| author_role | author |
| dc.creator.none.fl_str_mv | Phool Iqbal (12217770) Fateen Ata (12217764) Hassan Chaudhry (8666385) Bassam Muthanna (14777407) Hafiz Waqas Younas (21385562) Syed Ata ul Munamm (21385565) Rohit Sharma (286462) Kahtan Fadah (21385568) Shereen Elazzazy (9545774) Anas Hamad (9545771) Osama Said Abu Tabar (21385571) Nabil E. Omar (9545756) |
| dc.date.none.fl_str_mv | 2023-04-14T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1002/hsr2.1211 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Post_COVID_19_associated_multiorgan_complications_or_long_COVID_with_literature_review_and_management_strategy_discussion_A_meta_analysis/29098493 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Health sciences Epidemiology Public health COVID‐19 complications long COVID Meta‐analysis Post COVID‐19 SARS‐CoV‐2 sequelae |
| dc.title.none.fl_str_mv | Post‐COVID‐19‐associated multiorgan complications or “long COVID” with literature review and management strategy discussion: A meta‐analysis |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Objective</h3><p dir="ltr">To investigate the post‐COVID‐19 long‐term complications or long COVID of various organ systems in patients after 3 months of the infection, specifically before the Omicron variant, with comparative literature analysis.</p><h3>Methods</h3><p dir="ltr">A systemic literature search and meta‐analysis were conducted using multiple electronic databases (PubMed, Scopus, Cochrane library) with predefined search terms to identify eligible articles. Eligible studies reported long‐term complications of COVID‐19 infection before the Omicron variant infection. Case reports, case series, observational studies with cross‐sectional or prospective research design, case–control studies, and experimental studies that reported post‐COVID‐19 complications were included. The complications reported after 3 months after the recovery from COVID‐19 infection were included in the study.</p><h3>Results</h3><p dir="ltr">The total number of studies available for analysis was 34. The effect size (ES) for neurological complications was 29% with 95% confidence interval (CI): 19%–39%. ES for psychiatric complications was 24% with 95% CI: 7%–41%. ES was 9% for cardiac outcomes, with a 95% CI of 1%–18%. ES was 22%, 95% CI: 5%–39% for the gastrointestinal outcome. ES for musculoskeletal symptoms was 18% with 95% CI: 9%–28%. ES for pulmonary complications was 28% with 95% CI: 18%–37%. ES for dermatological complications was 25%, with a 95% CI of 23%–26%. ES for endocrine outcomes was 8%, with a 95% CI of 8%–9%. ES size for renal outcomes was 3% with a 95% CI of 1%–7%. At the same time, other miscellaneous uncategorized outcomes had ES of 39% with 95% CI of 21%–57%. Apart from analyzing COVID‐19 systemic complications outcomes, the ES for hospitalization and intensive care unit admissions were found to be 4%, 95% CI: 0%–7%, and 11% with 95% CI: 8%–14%.</p><h3>Conclusion</h3><p dir="ltr">By acquiring the data and statistically analyzing the post‐COVID‐19 complications during the prevalence of most virulent strains, this study has generated a different way of understanding COVID‐19 and its complications for better community health.</p><h2>Other Information</h2><p dir="ltr">Published in: Health Science Reports<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/hsr2.1211" target="_blank">https://dx.doi.org/10.1002/hsr2.1211</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_4dfbafafdabc5e5504ec1ed4474cee47 |
| identifier_str_mv | 10.1002/hsr2.1211 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/29098493 |
| publishDate | 2023 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Post‐COVID‐19‐associated multiorgan complications or “long COVID” with literature review and management strategy discussion: A meta‐analysisPhool Iqbal (12217770)Fateen Ata (12217764)Hassan Chaudhry (8666385)Bassam Muthanna (14777407)Hafiz Waqas Younas (21385562)Syed Ata ul Munamm (21385565)Rohit Sharma (286462)Kahtan Fadah (21385568)Shereen Elazzazy (9545774)Anas Hamad (9545771)Osama Said Abu Tabar (21385571)Nabil E. Omar (9545756)Biomedical and clinical sciencesClinical sciencesHealth sciencesEpidemiologyPublic healthCOVID‐19 complicationslong COVIDMeta‐analysisPost COVID‐19SARS‐CoV‐2 sequelae<h3>Objective</h3><p dir="ltr">To investigate the post‐COVID‐19 long‐term complications or long COVID of various organ systems in patients after 3 months of the infection, specifically before the Omicron variant, with comparative literature analysis.</p><h3>Methods</h3><p dir="ltr">A systemic literature search and meta‐analysis were conducted using multiple electronic databases (PubMed, Scopus, Cochrane library) with predefined search terms to identify eligible articles. Eligible studies reported long‐term complications of COVID‐19 infection before the Omicron variant infection. Case reports, case series, observational studies with cross‐sectional or prospective research design, case–control studies, and experimental studies that reported post‐COVID‐19 complications were included. The complications reported after 3 months after the recovery from COVID‐19 infection were included in the study.</p><h3>Results</h3><p dir="ltr">The total number of studies available for analysis was 34. The effect size (ES) for neurological complications was 29% with 95% confidence interval (CI): 19%–39%. ES for psychiatric complications was 24% with 95% CI: 7%–41%. ES was 9% for cardiac outcomes, with a 95% CI of 1%–18%. ES was 22%, 95% CI: 5%–39% for the gastrointestinal outcome. ES for musculoskeletal symptoms was 18% with 95% CI: 9%–28%. ES for pulmonary complications was 28% with 95% CI: 18%–37%. ES for dermatological complications was 25%, with a 95% CI of 23%–26%. ES for endocrine outcomes was 8%, with a 95% CI of 8%–9%. ES size for renal outcomes was 3% with a 95% CI of 1%–7%. At the same time, other miscellaneous uncategorized outcomes had ES of 39% with 95% CI of 21%–57%. Apart from analyzing COVID‐19 systemic complications outcomes, the ES for hospitalization and intensive care unit admissions were found to be 4%, 95% CI: 0%–7%, and 11% with 95% CI: 8%–14%.</p><h3>Conclusion</h3><p dir="ltr">By acquiring the data and statistically analyzing the post‐COVID‐19 complications during the prevalence of most virulent strains, this study has generated a different way of understanding COVID‐19 and its complications for better community health.</p><h2>Other Information</h2><p dir="ltr">Published in: Health Science Reports<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/hsr2.1211" target="_blank">https://dx.doi.org/10.1002/hsr2.1211</a></p>2023-04-14T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1002/hsr2.1211https://figshare.com/articles/journal_contribution/Post_COVID_19_associated_multiorgan_complications_or_long_COVID_with_literature_review_and_management_strategy_discussion_A_meta_analysis/29098493CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/290984932023-04-14T09:00:00Z |
| spellingShingle | Post‐COVID‐19‐associated multiorgan complications or “long COVID” with literature review and management strategy discussion: A meta‐analysis Phool Iqbal (12217770) Biomedical and clinical sciences Clinical sciences Health sciences Epidemiology Public health COVID‐19 complications long COVID Meta‐analysis Post COVID‐19 SARS‐CoV‐2 sequelae |
| status_str | publishedVersion |
| title | Post‐COVID‐19‐associated multiorgan complications or “long COVID” with literature review and management strategy discussion: A meta‐analysis |
| title_full | Post‐COVID‐19‐associated multiorgan complications or “long COVID” with literature review and management strategy discussion: A meta‐analysis |
| title_fullStr | Post‐COVID‐19‐associated multiorgan complications or “long COVID” with literature review and management strategy discussion: A meta‐analysis |
| title_full_unstemmed | Post‐COVID‐19‐associated multiorgan complications or “long COVID” with literature review and management strategy discussion: A meta‐analysis |
| title_short | Post‐COVID‐19‐associated multiorgan complications or “long COVID” with literature review and management strategy discussion: A meta‐analysis |
| title_sort | Post‐COVID‐19‐associated multiorgan complications or “long COVID” with literature review and management strategy discussion: A meta‐analysis |
| topic | Biomedical and clinical sciences Clinical sciences Health sciences Epidemiology Public health COVID‐19 complications long COVID Meta‐analysis Post COVID‐19 SARS‐CoV‐2 sequelae |