DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation

DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation

<p>Failure of the heat shock response is a key event that leads to insulin resistance and type 2 diabetes. We recently showed that DNAJB3 co-chaperone is downregulated in obese and diabetic patients and that physical exercise restores its normal expression with a significant improvement of the...

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Bibliographic Details
Main Author: Abdelilah Arredouani (10914455) (author)
Other Authors: Abdoulaye Diane (14152749) (author), Namat Khattab (14152752) (author), Ilham Bensmail (12204845) (author), Imad Aoude (14152755) (author), Mohamed Chikri (2243) (author), Ramzi Mohammad (3520061) (author), Abdul Badi Abou-Samra (9417977) (author), Mohammed Dehbi (14152758) (author)
Published: 2019
Subjects:
Biomedical and clinical sciences
Clinical sciences
Medical biochemistry and metabolomics
DNAJB3
Heat Shock
Response Insulin Resistance
Type 2 Diabetes
Obesity
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