Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative review
<p dir="ltr">Lower urinary tract symptoms (LUTS) are caused by higher tension at the bladder neck level (due to fibrosis or stiffness) or benign prostatic hyperplasia, which causes static obstruction of the bladder outlet. Both forms cause a group of symptoms such as hesitancy, inter...
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2022
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| _version_ | 1864513546038018048 |
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| author | Raed M. Al-Zoubi (2037490) |
| author2 | Mustafa Alwani (17787566) Omar M. Aboumarzouk (14779240) Mai Elaarag (17807390) Ahmad R. Al-Qudimat (17337808) Laxmi Ojha (20401967) Aksam Yassin (14779204) |
| author2_role | author author author author author author |
| author_facet | Raed M. Al-Zoubi (2037490) Mustafa Alwani (17787566) Omar M. Aboumarzouk (14779240) Mai Elaarag (17807390) Ahmad R. Al-Qudimat (17337808) Laxmi Ojha (20401967) Aksam Yassin (14779204) |
| author_role | author |
| dc.creator.none.fl_str_mv | Raed M. Al-Zoubi (2037490) Mustafa Alwani (17787566) Omar M. Aboumarzouk (14779240) Mai Elaarag (17807390) Ahmad R. Al-Qudimat (17337808) Laxmi Ojha (20401967) Aksam Yassin (14779204) |
| dc.date.none.fl_str_mv | 2022-09-06T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1080/13685538.2022.2118253 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Updates_on_androgen_replacement_therapy_and_lower_urinary_tract_symptoms_a_narrative_review/29413394 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Medical biochemistry and metabolomics LUTS BPH androgen; TRT hypogonadism |
| dc.title.none.fl_str_mv | Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative review |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Lower urinary tract symptoms (LUTS) are caused by higher tension at the bladder neck level (due to fibrosis or stiffness) or benign prostatic hyperplasia, which causes static obstruction of the bladder outlet. Both forms cause a group of symptoms such as hesitancy, intermittency, weak stream, nocturia, urine frequency, and urgency. Additionally, LUTS (obstructive or irritative symptoms) are common in elderly men with hypogonadism, identified as the reduced testes capability in producing sex steroids and sperm, and are categorized as testosterone deficiency. Even though the mode of action (MoA) of testosterone therapy (TTh) on hypogonadal men needs more researched and understanding, the effectiveness of TTh in the development of male genital organs has been reported in several studies. This review shows the latest updates of TTh in LUTS including potential adverse effects, advantages, and disadvantages.</p><h2>Other Information</h2><p dir="ltr">Published in: The Aging Male<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1080/13685538.2022.2118253" target="_blank">https://dx.doi.org/10.1080/13685538.2022.2118253</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_544a82cd463f5e51a79f985dc27af1de |
| identifier_str_mv | 10.1080/13685538.2022.2118253 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/29413394 |
| publishDate | 2022 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative reviewRaed M. Al-Zoubi (2037490)Mustafa Alwani (17787566)Omar M. Aboumarzouk (14779240)Mai Elaarag (17807390)Ahmad R. Al-Qudimat (17337808)Laxmi Ojha (20401967)Aksam Yassin (14779204)Biomedical and clinical sciencesClinical sciencesMedical biochemistry and metabolomicsLUTSBPHandrogen;TRThypogonadism<p dir="ltr">Lower urinary tract symptoms (LUTS) are caused by higher tension at the bladder neck level (due to fibrosis or stiffness) or benign prostatic hyperplasia, which causes static obstruction of the bladder outlet. Both forms cause a group of symptoms such as hesitancy, intermittency, weak stream, nocturia, urine frequency, and urgency. Additionally, LUTS (obstructive or irritative symptoms) are common in elderly men with hypogonadism, identified as the reduced testes capability in producing sex steroids and sperm, and are categorized as testosterone deficiency. Even though the mode of action (MoA) of testosterone therapy (TTh) on hypogonadal men needs more researched and understanding, the effectiveness of TTh in the development of male genital organs has been reported in several studies. This review shows the latest updates of TTh in LUTS including potential adverse effects, advantages, and disadvantages.</p><h2>Other Information</h2><p dir="ltr">Published in: The Aging Male<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1080/13685538.2022.2118253" target="_blank">https://dx.doi.org/10.1080/13685538.2022.2118253</a></p>2022-09-06T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1080/13685538.2022.2118253https://figshare.com/articles/journal_contribution/Updates_on_androgen_replacement_therapy_and_lower_urinary_tract_symptoms_a_narrative_review/29413394CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/294133942022-09-06T03:00:00Z |
| spellingShingle | Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative review Raed M. Al-Zoubi (2037490) Biomedical and clinical sciences Clinical sciences Medical biochemistry and metabolomics LUTS BPH androgen; TRT hypogonadism |
| status_str | publishedVersion |
| title | Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative review |
| title_full | Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative review |
| title_fullStr | Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative review |
| title_full_unstemmed | Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative review |
| title_short | Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative review |
| title_sort | Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative review |
| topic | Biomedical and clinical sciences Clinical sciences Medical biochemistry and metabolomics LUTS BPH androgen; TRT hypogonadism |