Open versus closed intramedullary nailing of femur shaft fractures in adults: a systematic review and meta-analysis
<h3>Purpose</h3><p dir="ltr">This systematic review and meta-analysis aimed to compare the outcomes of open- versus closed-reduction and intramedullary nailing (IMN) of adult femur shaft fractures.</p><h3>Methods</h3><p dir="ltr">Four dat...
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| مؤلفون آخرون: | , , , , , , |
| منشور في: |
2023
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| _version_ | 1864513530975223808 |
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| author | Loay A. Salman (14150322) |
| author2 | Abdallah Al-Ani (10687939) Mohammed F. A. Radi (17760267) Abedallah F. Abudalou (17760270) Omar M. Baroudi (17760273) Abdulla A. Ajaj (17760276) Mohamed Alkhayarin (17760279) Ghalib Ahmed (14146800) |
| author2_role | author author author author author author author |
| author_facet | Loay A. Salman (14150322) Abdallah Al-Ani (10687939) Mohammed F. A. Radi (17760267) Abedallah F. Abudalou (17760270) Omar M. Baroudi (17760273) Abdulla A. Ajaj (17760276) Mohamed Alkhayarin (17760279) Ghalib Ahmed (14146800) |
| author_role | author |
| dc.creator.none.fl_str_mv | Loay A. Salman (14150322) Abdallah Al-Ani (10687939) Mohammed F. A. Radi (17760267) Abedallah F. Abudalou (17760270) Omar M. Baroudi (17760273) Abdulla A. Ajaj (17760276) Mohamed Alkhayarin (17760279) Ghalib Ahmed (14146800) |
| dc.date.none.fl_str_mv | 2023-03-03T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1007/s00264-023-05740-x |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Open_versus_closed_intramedullary_nailing_of_femur_shaft_fractures_in_adults_a_systematic_review_and_meta-analysis/24967146 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Mathematical sciences Statistics Open reduction Closed reduction Intramedullary nail Femur Fractures |
| dc.title.none.fl_str_mv | Open versus closed intramedullary nailing of femur shaft fractures in adults: a systematic review and meta-analysis |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Purpose</h3><p dir="ltr">This systematic review and meta-analysis aimed to compare the outcomes of open- versus closed-reduction and intramedullary nailing (IMN) of adult femur shaft fractures.</p><h3>Methods</h3><p dir="ltr">Four databases were searched from inception until July 2022 for original studies that compared the outcomes of IMN following open-reduction versus closed-reduction technique. The primary outcome was the union rate; the secondary outcomes were time to union, nonunion, malalignment, revision, and infection. This review was conducted in line with PRISMA guidelines.</p><h3>Results</h3><p dir="ltr">A total of 12 studies with 1299 (1346 IMN cases) patients were included, with a mean age of 32.3 ± 3.25. The average follow-up was 2.3 ± 1.45 years. There was a statistically significant difference in union rate (OR, 0.66; 95% CI, 0.45–0.97; p-value, 0.0352), nonunion (OR, 2.06; 95% CI, 1.23–3.44; p-value, 0.0056), and infection rate (OR, 1.94; 95% CI, 1.16–3.25; p-value, 0.0114) between the open-reduction and closed-reduction groups in favour of the latter. However, malalignment was significantly higher in the closed-reduction group (OR, 0.32; 95% CI, 0.16–0.64; p-value, 0.0012), whereas time to union and revision rates were similar (p = NS).</p><h3>Conclusion</h3><p dir="ltr">This study showed that closed-reduction and IMN had more favourable union rate, nonunion, and infection rates than the open-reduction group, yet malalignment was significantly less in the open-reduction group. Moreover, time to union and revision rates were comparable. However, these results must be interpreted in context due to confounding effects and the lack of high-quality studies.</p><h2>Other Information</h2><p dir="ltr">Published in: International Orthopaedics<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s00264-023-05740-x" target="_blank">https://dx.doi.org/10.1007/s00264-023-05740-x</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_546332ea1507776a2064b563d23448ce |
| identifier_str_mv | 10.1007/s00264-023-05740-x |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/24967146 |
| publishDate | 2023 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Open versus closed intramedullary nailing of femur shaft fractures in adults: a systematic review and meta-analysisLoay A. Salman (14150322)Abdallah Al-Ani (10687939)Mohammed F. A. Radi (17760267)Abedallah F. Abudalou (17760270)Omar M. Baroudi (17760273)Abdulla A. Ajaj (17760276)Mohamed Alkhayarin (17760279)Ghalib Ahmed (14146800)Biomedical and clinical sciencesClinical sciencesMathematical sciencesStatisticsOpen reductionClosed reductionIntramedullary nailFemurFractures<h3>Purpose</h3><p dir="ltr">This systematic review and meta-analysis aimed to compare the outcomes of open- versus closed-reduction and intramedullary nailing (IMN) of adult femur shaft fractures.</p><h3>Methods</h3><p dir="ltr">Four databases were searched from inception until July 2022 for original studies that compared the outcomes of IMN following open-reduction versus closed-reduction technique. The primary outcome was the union rate; the secondary outcomes were time to union, nonunion, malalignment, revision, and infection. This review was conducted in line with PRISMA guidelines.</p><h3>Results</h3><p dir="ltr">A total of 12 studies with 1299 (1346 IMN cases) patients were included, with a mean age of 32.3 ± 3.25. The average follow-up was 2.3 ± 1.45 years. There was a statistically significant difference in union rate (OR, 0.66; 95% CI, 0.45–0.97; p-value, 0.0352), nonunion (OR, 2.06; 95% CI, 1.23–3.44; p-value, 0.0056), and infection rate (OR, 1.94; 95% CI, 1.16–3.25; p-value, 0.0114) between the open-reduction and closed-reduction groups in favour of the latter. However, malalignment was significantly higher in the closed-reduction group (OR, 0.32; 95% CI, 0.16–0.64; p-value, 0.0012), whereas time to union and revision rates were similar (p = NS).</p><h3>Conclusion</h3><p dir="ltr">This study showed that closed-reduction and IMN had more favourable union rate, nonunion, and infection rates than the open-reduction group, yet malalignment was significantly less in the open-reduction group. Moreover, time to union and revision rates were comparable. However, these results must be interpreted in context due to confounding effects and the lack of high-quality studies.</p><h2>Other Information</h2><p dir="ltr">Published in: International Orthopaedics<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s00264-023-05740-x" target="_blank">https://dx.doi.org/10.1007/s00264-023-05740-x</a></p>2023-03-03T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s00264-023-05740-xhttps://figshare.com/articles/journal_contribution/Open_versus_closed_intramedullary_nailing_of_femur_shaft_fractures_in_adults_a_systematic_review_and_meta-analysis/24967146CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/249671462023-03-03T03:00:00Z |
| spellingShingle | Open versus closed intramedullary nailing of femur shaft fractures in adults: a systematic review and meta-analysis Loay A. Salman (14150322) Biomedical and clinical sciences Clinical sciences Mathematical sciences Statistics Open reduction Closed reduction Intramedullary nail Femur Fractures |
| status_str | publishedVersion |
| title | Open versus closed intramedullary nailing of femur shaft fractures in adults: a systematic review and meta-analysis |
| title_full | Open versus closed intramedullary nailing of femur shaft fractures in adults: a systematic review and meta-analysis |
| title_fullStr | Open versus closed intramedullary nailing of femur shaft fractures in adults: a systematic review and meta-analysis |
| title_full_unstemmed | Open versus closed intramedullary nailing of femur shaft fractures in adults: a systematic review and meta-analysis |
| title_short | Open versus closed intramedullary nailing of femur shaft fractures in adults: a systematic review and meta-analysis |
| title_sort | Open versus closed intramedullary nailing of femur shaft fractures in adults: a systematic review and meta-analysis |
| topic | Biomedical and clinical sciences Clinical sciences Mathematical sciences Statistics Open reduction Closed reduction Intramedullary nail Femur Fractures |