Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy

Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy

<h2>Background</h2><p dir="ltr">The mechanism of tumor immune escape and progression in colorectal cancer (CRC) is widely investigated in-vitro to help understand and identify agents that might play a crucial role in response to treatment and improve the overall survival...

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Main Author: Nassiba Taib (14557385) (author)
Other Authors: Maysaloun Merhi (4246147) (author), Varghese Inchakalody (15263530) (author), Sarra Mestiri (14557379) (author), Shereena Hydrose (14442135) (author), Karama Makni-Maalej (15263533) (author), Afsheen Raza (492657) (author), Fairooz Sahir (6595517) (author), Fouad Azizi (11835843) (author), Parveen B. Nizamuddin (14590613) (author), Queenie Fernandes (14557388) (author), Zeenath Safira K. M. Yoosuf (15263536) (author), Salam Almoghrabi (15263539) (author), Lobna Al-Zaidan (14557394) (author), Alaaeldin Shablak (14778097) (author), Shahab Uddin (154400) (author), Cristina Maccalli (2632465) (author), Mohammed Ussama Al Homsi (15263542) (author), Said Dermime (79420) (author)
Published: 2023
Subjects:
Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Reproductive medicine
Colorectal cancer
Decitabine
NY-ESO-1
PD-L1
Stemness markers
Chemoresistance
Immune escape
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