Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report

<h3>Key Clinical Message</h3><p dir="ltr">This report documents the treatment of a 41‐year‐old male with sickle cell disease (SCD) and repeated stuttering priapism using crizanlizumab, which alleviated the priapism but induced a significant vaso‐occlusive crisis during th...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Mohammed Abdulgayoom (14777791) (author)
مؤلفون آخرون: Mohammad S. Afana (17933354) (author), Awni Alshurafa (15468195) (author), Mohamed A. Yassin (8361183) (author)
منشور في: 2024
الموضوعات:
الوسوم: إضافة وسم
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author Mohammed Abdulgayoom (14777791)
author2 Mohammad S. Afana (17933354)
Awni Alshurafa (15468195)
Mohamed A. Yassin (8361183)
author2_role author
author
author
author_facet Mohammed Abdulgayoom (14777791)
Mohammad S. Afana (17933354)
Awni Alshurafa (15468195)
Mohamed A. Yassin (8361183)
author_role author
dc.creator.none.fl_str_mv Mohammed Abdulgayoom (14777791)
Mohammad S. Afana (17933354)
Awni Alshurafa (15468195)
Mohamed A. Yassin (8361183)
dc.date.none.fl_str_mv 2024-05-10T09:00:00Z
dc.identifier.none.fl_str_mv 10.1002/ccr3.8585
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Potential_efficacy_of_crizanlizumab_in_treating_priapism_in_sickle_cell_disease_A_case_report/29715482
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Cardiovascular medicine and haematology
Clinical sciences
acute chest syndrome
crizanlizumab
infusion-related reactions
pain crises
priapism
vaso- occlusive crises
dc.title.none.fl_str_mv Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Key Clinical Message</h3><p dir="ltr">This report documents the treatment of a 41‐year‐old male with sickle cell disease (SCD) and repeated stuttering priapism using crizanlizumab, which alleviated the priapism but induced a significant vaso‐occlusive crisis during the second infusion. Encouragingly, no subsequent vaso‐occlusive crises occurred. However, the potential for infusion‐related adverse events warrants close supervision. Further research is necessary to explore its full benefits on priapism management.</p><h2>Other Information</h2><p dir="ltr">Published in: Clinical Case Reports<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/ccr3.8585" target="_blank">https://dx.doi.org/10.1002/ccr3.8585</a></p>
eu_rights_str_mv openAccess
id Manara2_557679b81242a8fce1cddcbeaea573f5
identifier_str_mv 10.1002/ccr3.8585
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/29715482
publishDate 2024
repository.mail.fl_str_mv
repository.name.fl_str_mv
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rights_invalid_str_mv CC BY 4.0
spelling Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case reportMohammed Abdulgayoom (14777791)Mohammad S. Afana (17933354)Awni Alshurafa (15468195)Mohamed A. Yassin (8361183)Biomedical and clinical sciencesCardiovascular medicine and haematologyClinical sciencesacute chest syndromecrizanlizumabinfusion-related reactionspain crisespriapismvaso- occlusive crises<h3>Key Clinical Message</h3><p dir="ltr">This report documents the treatment of a 41‐year‐old male with sickle cell disease (SCD) and repeated stuttering priapism using crizanlizumab, which alleviated the priapism but induced a significant vaso‐occlusive crisis during the second infusion. Encouragingly, no subsequent vaso‐occlusive crises occurred. However, the potential for infusion‐related adverse events warrants close supervision. Further research is necessary to explore its full benefits on priapism management.</p><h2>Other Information</h2><p dir="ltr">Published in: Clinical Case Reports<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/ccr3.8585" target="_blank">https://dx.doi.org/10.1002/ccr3.8585</a></p>2024-05-10T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1002/ccr3.8585https://figshare.com/articles/journal_contribution/Potential_efficacy_of_crizanlizumab_in_treating_priapism_in_sickle_cell_disease_A_case_report/29715482CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/297154822024-05-10T09:00:00Z
spellingShingle Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report
Mohammed Abdulgayoom (14777791)
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Clinical sciences
acute chest syndrome
crizanlizumab
infusion-related reactions
pain crises
priapism
vaso- occlusive crises
status_str publishedVersion
title Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report
title_full Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report
title_fullStr Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report
title_full_unstemmed Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report
title_short Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report
title_sort Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report
topic Biomedical and clinical sciences
Cardiovascular medicine and haematology
Clinical sciences
acute chest syndrome
crizanlizumab
infusion-related reactions
pain crises
priapism
vaso- occlusive crises