Human induced pluripotent stem cell line (QBRIi013-A) derivation from a 6-year-old female diagnosed with Autism spectrum disorder (ASD) and intellectual disability (ID)
<p dir="ltr">Autism spectrum disorder (ASD) is a childhood-onset neurodevelopmental disorder characterized by social interaction, behavior, and communication challenges. Here, we generated an induced pluripotent stem cell (iPSC) line, QBRIi013-A using a non-integrating Sendai virus f...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , |
| منشور في: |
2021
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| الموضوعات: | |
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| _version_ | 1864513547820597248 |
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| author | Ahmed K. Elsayed (13275302) |
| author2 | Salam Salloum-Asfar (656363) Sara A. Abdulla (13902015) |
| author2_role | author author |
| author_facet | Ahmed K. Elsayed (13275302) Salam Salloum-Asfar (656363) Sara A. Abdulla (13902015) |
| author_role | author |
| dc.creator.none.fl_str_mv | Ahmed K. Elsayed (13275302) Salam Salloum-Asfar (656363) Sara A. Abdulla (13902015) |
| dc.date.none.fl_str_mv | 2021-10-01T00:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.scr.2021.102500 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Human_induced_pluripotent_stem_cell_line_QBRIi013-A_derivation_from_a_6-year-old_female_diagnosed_with_Autism_spectrum_disorder_ASD_and_intellectual_disability_ID_/24420445 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Medical biotechnology Neurosciences Human stem cell (QBRIi013-A) Autism spectrum disorder (ASD) intellectual disability (ID) Neurological Disorders Research Center (QBRI) |
| dc.title.none.fl_str_mv | Human induced pluripotent stem cell line (QBRIi013-A) derivation from a 6-year-old female diagnosed with Autism spectrum disorder (ASD) and intellectual disability (ID) |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Autism spectrum disorder (ASD) is a childhood-onset neurodevelopmental disorder characterized by social interaction, behavior, and communication challenges. Here, we generated an induced pluripotent stem cell (iPSC) line, QBRIi013-A using a non-integrating Sendai virus from a 6-year-old female diagnosed with ASD and intellectual disability. The QBRIi013-A cell line was fully characterized and exhibited a pluripotency capacity and trilineage differentiation potential. Furthermore, it showed normal karyotype and genetic identity to the patient’s PBMCs. Consequently, this iPSC line provides a valuable cell model in understanding the molecular mechanism underlying the complexities of ASD pathogenesis.</p><h2>Other Information</h2><p dir="ltr">Published in: Stem Cell Research<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.scr.2021.102500" target="_blank">https://dx.doi.org/10.1016/j.scr.2021.102500</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_58dff62af8cc6032090044314b6da3b2 |
| identifier_str_mv | 10.1016/j.scr.2021.102500 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/24420445 |
| publishDate | 2021 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Human induced pluripotent stem cell line (QBRIi013-A) derivation from a 6-year-old female diagnosed with Autism spectrum disorder (ASD) and intellectual disability (ID)Ahmed K. Elsayed (13275302)Salam Salloum-Asfar (656363)Sara A. Abdulla (13902015)Biomedical and clinical sciencesMedical biotechnologyNeurosciencesHumanstem cell(QBRIi013-A)Autism spectrum disorder (ASD)intellectual disability (ID)Neurological Disorders Research Center (QBRI)<p dir="ltr">Autism spectrum disorder (ASD) is a childhood-onset neurodevelopmental disorder characterized by social interaction, behavior, and communication challenges. Here, we generated an induced pluripotent stem cell (iPSC) line, QBRIi013-A using a non-integrating Sendai virus from a 6-year-old female diagnosed with ASD and intellectual disability. The QBRIi013-A cell line was fully characterized and exhibited a pluripotency capacity and trilineage differentiation potential. Furthermore, it showed normal karyotype and genetic identity to the patient’s PBMCs. Consequently, this iPSC line provides a valuable cell model in understanding the molecular mechanism underlying the complexities of ASD pathogenesis.</p><h2>Other Information</h2><p dir="ltr">Published in: Stem Cell Research<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.scr.2021.102500" target="_blank">https://dx.doi.org/10.1016/j.scr.2021.102500</a></p>2021-10-01T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.scr.2021.102500https://figshare.com/articles/journal_contribution/Human_induced_pluripotent_stem_cell_line_QBRIi013-A_derivation_from_a_6-year-old_female_diagnosed_with_Autism_spectrum_disorder_ASD_and_intellectual_disability_ID_/24420445CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/244204452021-10-01T00:00:00Z |
| spellingShingle | Human induced pluripotent stem cell line (QBRIi013-A) derivation from a 6-year-old female diagnosed with Autism spectrum disorder (ASD) and intellectual disability (ID) Ahmed K. Elsayed (13275302) Biomedical and clinical sciences Medical biotechnology Neurosciences Human stem cell (QBRIi013-A) Autism spectrum disorder (ASD) intellectual disability (ID) Neurological Disorders Research Center (QBRI) |
| status_str | publishedVersion |
| title | Human induced pluripotent stem cell line (QBRIi013-A) derivation from a 6-year-old female diagnosed with Autism spectrum disorder (ASD) and intellectual disability (ID) |
| title_full | Human induced pluripotent stem cell line (QBRIi013-A) derivation from a 6-year-old female diagnosed with Autism spectrum disorder (ASD) and intellectual disability (ID) |
| title_fullStr | Human induced pluripotent stem cell line (QBRIi013-A) derivation from a 6-year-old female diagnosed with Autism spectrum disorder (ASD) and intellectual disability (ID) |
| title_full_unstemmed | Human induced pluripotent stem cell line (QBRIi013-A) derivation from a 6-year-old female diagnosed with Autism spectrum disorder (ASD) and intellectual disability (ID) |
| title_short | Human induced pluripotent stem cell line (QBRIi013-A) derivation from a 6-year-old female diagnosed with Autism spectrum disorder (ASD) and intellectual disability (ID) |
| title_sort | Human induced pluripotent stem cell line (QBRIi013-A) derivation from a 6-year-old female diagnosed with Autism spectrum disorder (ASD) and intellectual disability (ID) |
| topic | Biomedical and clinical sciences Medical biotechnology Neurosciences Human stem cell (QBRIi013-A) Autism spectrum disorder (ASD) intellectual disability (ID) Neurological Disorders Research Center (QBRI) |