RNA-Seq Analysis of Colorectal Tumor-Infiltrating Myeloid-Derived Suppressor Cell Subsets Revealed Gene Signatures of Poor Prognosis

RNA-Seq Analysis of Colorectal Tumor-Infiltrating Myeloid-Derived Suppressor Cell Subsets Revealed Gene Signatures of Poor Prognosis

<p dir="ltr">Elevated levels of myeloid-derived suppressor cells (MDSCs), including polymorphonuclear MDSCs (PMN-MDSCs) and immature MDSCs (I-MDSCs), are usually associated with disease progression in cancer patients, including colorectal cancer (CRC). However, biological mechanisms...

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Bibliographic Details
Main Author: Reem Saleh (3513056) (author)
Other Authors: Varun Sasidharan Nair (5396393) (author), Mahmood Al-Dhaheri (9621035) (author), Mahwish Khawar (9621038) (author), Mohamed Abu Nada (8309784) (author), Nehad M. Alajez (7397276) (author), Eyad Elkord (5396390) (author)
Published: 2020
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Immunology
Medical biochemistry and metabolomics
Oncology and carcinogenesis
myeloid-derived suppressor cells
colorectal cancer
transcriptomic profiling
metabolism
signaling pathways
immune responses
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