Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer

Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer

<p>Despite recent advances in colorectal cancer (CRC) treatment, a large proportion of patients show limited responses to therapies, especially in advanced stages. There is an urgent need to identify prognostic biomarkers and/or therapeutic targets in advanced stages, aiming to improve the eff...

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Bibliographic Details
Main Author: Reem Saleh (3513056) (author)
Other Authors: Rowaida Z. Taha (8854754) (author), Salman M. Toor (8854751) (author), Varun Sasidharan Nair (5396393) (author), Khaled Murshed (8309781) (author), Mahwish Khawar (9621038) (author), Mahmood Al-Dhaheri (9621035) (author), Mahir Abdulla Petkar (14150211) (author), Mohamed Abu Nada (8309784) (author), Eyad Elkord (5396390) (author)
Published: 2020
Subjects:
Biomedical and clinical sciences
Immunology
Oncology and carcinogenesis
Colorectal cancer
Immune checkpoints
T cell exhaustion
Prognostic biomarker
Therapeutic target
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