iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes
<p dir="ltr">Recently, we reported that forkhead box A2 (FOXA2) is required for the development of human pancreatic α- and β-cells. However, whether miRNAs play a role in regulating pancreatic genes during pancreatic development in the absence of FOXA2 expression is largely unknown....
Saved in:
| Main Author: | Noura Aldous (15429873) (author) |
|---|---|
| Other Authors: | Ahmed K. Elsayed (13275302) (author), Nehad M. Alajez (7397276) (author), Essam M. Abdelalim (5768072) (author) |
| Published: |
2023
|
| Subjects: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes
by: Noura Aldous (15429873)
Published: (2023) -
Identifying miRNA Signatures Associated with Pancreatic Islet Dysfunction in a FOXA2-Deficient iPSC Model
by: Ahmed K. Elsayed (13275302)
Published: (2024) -
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
by: Noura Aldous (15429873)
Published: (2024) -
Genome-wide differential expression profiling of long non-coding RNAs in FOXA2 knockout iPSC-derived pancreatic cells
by: Ahmed K. Elsayed (13275302)
Published: (2023) -
OutSingle: a novel method of detecting and injecting outliers in RNA-Seq count data using the optimal hard threshold for singular values
by: Edin Salkovic (16891479)
Published: (2023)