DNA methylation signatures in Blood DNA of Hutchinson–Gilford Progeria syndrome

DNA methylation signatures in Blood DNA of Hutchinson–Gilford Progeria syndrome

<p dir="ltr">Hutchinson–Gilford Progeria Syndrome (HGPS) is an extremely rare genetic disorder caused by mutations in the <i>LMNA</i> gene and characterized by premature and accelerated aging beginning in childhood. In this study, we performed the first genome-wide methyl...

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Bibliographic Details
Main Author: Yosra Bejaoui (8552574) (author)
Other Authors: Aleem Razzaq (14779189) (author), Noha A. Yousri (1392577) (author), Junko Oshima (1626) (author), Andre Megarbane (3485465) (author), Abeer Qannan (14779192) (author), Ramya Potabattula (4401160) (author), Tanvir Alam (638619) (author), George M. Martin (14779195) (author), Henning F. Horn (14152938) (author), Thomas Haaf (342924) (author), Steve Horvath (28847) (author), Nady El Hajj (686554) (author)
Published: 2022
Subjects:
Biological sciences
Biochemistry and cell biology
Genetics
Biomedical and clinical sciences
Clinical sciences
accelerated aging
DNA methylation
epigenetic clock
Hutchinson–Gilford Progeria syndrome
progeroid laminopathies
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