Oxygen therapy in preterm infants: recommendations for practice
<p dir="ltr">Oxygen is one of the most commonly used therapies in neonatology but optimum oxygen saturations for preterm infants have been debated for the past 50 years. The history of oxygen use in this population and multiple clinical trials over the years have shown that liberal o...
محفوظ في:
| المؤلف الرئيسي: | |
|---|---|
| مؤلفون آخرون: | , , |
| منشور في: |
2020
|
| الموضوعات: | |
| الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|
| _version_ | 1864513559444062208 |
|---|---|
| author | Sanoj. K.M. Ali (17058036) |
| author2 | Nancy Mohammed (17058039) Nadia Qureshi (17058042) Samir Gupta (584529) |
| author2_role | author author author |
| author_facet | Sanoj. K.M. Ali (17058036) Nancy Mohammed (17058039) Nadia Qureshi (17058042) Samir Gupta (584529) |
| author_role | author |
| dc.creator.none.fl_str_mv | Sanoj. K.M. Ali (17058036) Nancy Mohammed (17058039) Nadia Qureshi (17058042) Samir Gupta (584529) |
| dc.date.none.fl_str_mv | 2020-11-17T00:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.paed.2020.10.001 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Oxygen_therapy_in_preterm_infants_recommendations_for_practice/24210654 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Paediatrics bronchopulmonary dysplasia hyperoxia hypoxia oxygen preterm retinopathy of prematurity saturation targeting |
| dc.title.none.fl_str_mv | Oxygen therapy in preterm infants: recommendations for practice |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Oxygen is one of the most commonly used therapies in neonatology but optimum oxygen saturations for preterm infants have been debated for the past 50 years. The history of oxygen use in this population and multiple clinical trials over the years have shown that liberal oxygen administration is associated with retinopathy of prematurity (ROP) and bronchopulmonary dysplasia (BPD) whereas restrictive use results in increased mortality and neurodisability. Pulse oximetry (SpO<sub>2</sub>) is a bedside tool to guide the fraction of inspired oxygen (FiO<sub>2</sub>) delivered to the patient, and is the current standard of care for continuous monitoring. Although evidence favours targeting predetermined oxygen saturation ranges, achieving this goal consistently in clinical practice has been challenging due to intrinsic pulmonary immaturity, the need for respiratory support therapies and factors relating to the bedside caregivers ability to adjust FiO<sub>2</sub>. This review article focuses on the difficulties of titrating oxygen therapy in this vulnerable group and provides recommendations for the best practice based on up to date evidence.</p><h2>Other Information</h2><p dir="ltr">Published in: Paediatrics and Child Health<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.paed.2020.10.001" target="_blank">https://dx.doi.org/10.1016/j.paed.2020.10.001</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_6800a9e5c9ede6ff3a3378c24425bdbb |
| identifier_str_mv | 10.1016/j.paed.2020.10.001 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/24210654 |
| publishDate | 2020 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Oxygen therapy in preterm infants: recommendations for practiceSanoj. K.M. Ali (17058036)Nancy Mohammed (17058039)Nadia Qureshi (17058042)Samir Gupta (584529)Biomedical and clinical sciencesClinical sciencesPaediatricsbronchopulmonary dysplasiahyperoxiahypoxiaoxygenpretermretinopathy of prematuritysaturation targeting<p dir="ltr">Oxygen is one of the most commonly used therapies in neonatology but optimum oxygen saturations for preterm infants have been debated for the past 50 years. The history of oxygen use in this population and multiple clinical trials over the years have shown that liberal oxygen administration is associated with retinopathy of prematurity (ROP) and bronchopulmonary dysplasia (BPD) whereas restrictive use results in increased mortality and neurodisability. Pulse oximetry (SpO<sub>2</sub>) is a bedside tool to guide the fraction of inspired oxygen (FiO<sub>2</sub>) delivered to the patient, and is the current standard of care for continuous monitoring. Although evidence favours targeting predetermined oxygen saturation ranges, achieving this goal consistently in clinical practice has been challenging due to intrinsic pulmonary immaturity, the need for respiratory support therapies and factors relating to the bedside caregivers ability to adjust FiO<sub>2</sub>. This review article focuses on the difficulties of titrating oxygen therapy in this vulnerable group and provides recommendations for the best practice based on up to date evidence.</p><h2>Other Information</h2><p dir="ltr">Published in: Paediatrics and Child Health<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.paed.2020.10.001" target="_blank">https://dx.doi.org/10.1016/j.paed.2020.10.001</a></p>2020-11-17T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.paed.2020.10.001https://figshare.com/articles/journal_contribution/Oxygen_therapy_in_preterm_infants_recommendations_for_practice/24210654CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/242106542020-11-17T00:00:00Z |
| spellingShingle | Oxygen therapy in preterm infants: recommendations for practice Sanoj. K.M. Ali (17058036) Biomedical and clinical sciences Clinical sciences Paediatrics bronchopulmonary dysplasia hyperoxia hypoxia oxygen preterm retinopathy of prematurity saturation targeting |
| status_str | publishedVersion |
| title | Oxygen therapy in preterm infants: recommendations for practice |
| title_full | Oxygen therapy in preterm infants: recommendations for practice |
| title_fullStr | Oxygen therapy in preterm infants: recommendations for practice |
| title_full_unstemmed | Oxygen therapy in preterm infants: recommendations for practice |
| title_short | Oxygen therapy in preterm infants: recommendations for practice |
| title_sort | Oxygen therapy in preterm infants: recommendations for practice |
| topic | Biomedical and clinical sciences Clinical sciences Paediatrics bronchopulmonary dysplasia hyperoxia hypoxia oxygen preterm retinopathy of prematurity saturation targeting |