AMP-Activated Protein Kinase Is Essential for the Maintenance of Energy Levels during Synaptic Activation

AMP-Activated Protein Kinase Is Essential for the Maintenance of Energy Levels during Synaptic Activation

<p dir="ltr">Although the brain accounts for only 2% of the total body mass, it consumes the most energy. Neuronal metabolism is tightly controlled, but it remains poorly understood how neurons meet their energy demands to sustain synaptic transmission. Here we provide evidence that...

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Bibliographic Details
Main Author: Claudia Marinangeli (18711536) (author)
Other Authors: Sébastien Didier (18711538) (author), Tariq Ahmed (5768081) (author), Raphaelle Caillerez (18711541) (author), Manon Domise (18711543) (author), Charlotte Laloux (2586481) (author), Séverine Bégard (373773) (author), Sébastien Carrier (589820) (author), Morvane Colin (589821) (author), Philippe Marchetti (188456) (author), Bart Ghesquière (170156) (author), Detlef Balschun (8096618) (author), Luc Buée (142079) (author), Jérôme Kluza (18336205) (author), Valérie Vingtdeux (658327) (author)
Published: 2018
Subjects:
Biomedical and clinical sciences
Neurosciences
Alzheimer's disease
Cognitive impairments
Synaptic activation
Neuronal plasticity
Neuroenergetic regulation
Deregulation
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