Molecular pattern of acquiring upper respiratory infection

<p dir="ltr">Upper respiratory tract infections (URIs) are a significant public health concern. Human behavior plays a crucial role in how often infected individuals come into contact with susceptible individuals. Among the key factors influencing the seasonality of these infections,...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي: Mohamed A. Hendaus (9401919) (author)
منشور في: 2026
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author Mohamed A. Hendaus (9401919)
author_facet Mohamed A. Hendaus (9401919)
author_role author
dc.creator.none.fl_str_mv Mohamed A. Hendaus (9401919)
dc.date.none.fl_str_mv 2026-02-06T03:00:00Z
dc.identifier.none.fl_str_mv 10.3389/fmed.2026.1768374
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Molecular_pattern_of_acquiring_upper_respiratory_infection/32033331
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Immunology
Health sciences
Epidemiology
Public health
cold
extracellular vesicle swarms
immunity
upper respiratory infection
winter
dc.title.none.fl_str_mv Molecular pattern of acquiring upper respiratory infection
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">Upper respiratory tract infections (URIs) are a significant public health concern. Human behavior plays a crucial role in how often infected individuals come into contact with susceptible individuals. Among the key factors influencing the seasonality of these infections, variations in temperature and absolute humidity are critical elements driving the increase in respiratory virus infections, particularly during the winter months. Traditionally, it has been believed that cold and flu viruses thrive in winter mainly because falling temperatures lead to people spending more time indoors, which facilitates easier transmission. However, compelling evidence suggests that biological factors also contribute to the increased risk of illness in colder weather. Recent studies indicate that active mucosal defenses against bacteria extend into the mucus itself, aided by the epithelial release of antimicrobial extracellular vesicle (EV) swarms. Unfortunately, these studies have also shown that EVs are significantly weakened by exposure to cold environments.</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: Frontiers in Medicine<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fmed.2026.1768374" target="_blank">https://dx.doi.org/10.3389/fmed.2026.1768374</a></p>
eu_rights_str_mv openAccess
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identifier_str_mv 10.3389/fmed.2026.1768374
network_acronym_str Manara2
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oai_identifier_str oai:figshare.com:article/32033331
publishDate 2026
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spelling Molecular pattern of acquiring upper respiratory infectionMohamed A. Hendaus (9401919)Biomedical and clinical sciencesImmunologyHealth sciencesEpidemiologyPublic healthcoldextracellular vesicle swarmsimmunityupper respiratory infectionwinter<p dir="ltr">Upper respiratory tract infections (URIs) are a significant public health concern. Human behavior plays a crucial role in how often infected individuals come into contact with susceptible individuals. Among the key factors influencing the seasonality of these infections, variations in temperature and absolute humidity are critical elements driving the increase in respiratory virus infections, particularly during the winter months. Traditionally, it has been believed that cold and flu viruses thrive in winter mainly because falling temperatures lead to people spending more time indoors, which facilitates easier transmission. However, compelling evidence suggests that biological factors also contribute to the increased risk of illness in colder weather. Recent studies indicate that active mucosal defenses against bacteria extend into the mucus itself, aided by the epithelial release of antimicrobial extracellular vesicle (EV) swarms. Unfortunately, these studies have also shown that EVs are significantly weakened by exposure to cold environments.</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: Frontiers in Medicine<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fmed.2026.1768374" target="_blank">https://dx.doi.org/10.3389/fmed.2026.1768374</a></p>2026-02-06T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.3389/fmed.2026.1768374https://figshare.com/articles/journal_contribution/Molecular_pattern_of_acquiring_upper_respiratory_infection/32033331CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/320333312026-02-06T03:00:00Z
spellingShingle Molecular pattern of acquiring upper respiratory infection
Mohamed A. Hendaus (9401919)
Biomedical and clinical sciences
Immunology
Health sciences
Epidemiology
Public health
cold
extracellular vesicle swarms
immunity
upper respiratory infection
winter
status_str publishedVersion
title Molecular pattern of acquiring upper respiratory infection
title_full Molecular pattern of acquiring upper respiratory infection
title_fullStr Molecular pattern of acquiring upper respiratory infection
title_full_unstemmed Molecular pattern of acquiring upper respiratory infection
title_short Molecular pattern of acquiring upper respiratory infection
title_sort Molecular pattern of acquiring upper respiratory infection
topic Biomedical and clinical sciences
Immunology
Health sciences
Epidemiology
Public health
cold
extracellular vesicle swarms
immunity
upper respiratory infection
winter