Distinct antibody repertoires against endemic human coronaviruses in children and adults

Distinct antibody repertoires against endemic human coronaviruses in children and adults

<p dir="ltr">Four endemic human coronaviruses (HCoVs) are commonly associated with acute respiratory infection in humans. B cell responses to these “common cold” viruses remain incompletely understood. Here we report a comprehensive analysis of CoV-specific antibody repertoires in 23...

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Main Author: Taushif Khan (691254) (author)
Other Authors: Mahbuba Rahman (198499) (author), Fatima Al Ali (13210926) (author), Susie S.Y. Huang (18282292) (author), Manar Ata (9046473) (author), Qian Zhang (49333) (author), Paul Bastard (12967485) (author), Zhiyong Liu (160339) (author), Emmanuelle Jouanguy (64694) (author), Vivien Beziat (18508176) (author), Aurélie Cobat (2160433) (author), Gheyath K. Nasrallah (9200525) (author), Hadi M. Yassine (4675846) (author), Maria K. Smatti (4675852) (author), Amira Saeed (14152857) (author), Isabelle Vandernoot (18508179) (author), Jean-Christophe Goffard (5913116) (author), Guillaume Smits (4260148) (author), Isabelle Migeotte (245039) (author), Filomeen Haerynck (5913119) (author), Isabelle Meyts (8475399) (author), Laurent Abel (69833) (author), Jean-Laurent Casanova (64712) (author), Mohammad R. Hasan (13777597) (author), Nico Marr (349853) (author)
Published: 2021
Subjects:
Biomedical and clinical sciences
Clinical sciences
Immunology
Endemic human coronaviruses (HCoVs)
Acute respiratory infection
B cell responses
Common cold viruses
Antibody repertoires
Phage immunoprecipitation sequencing
Seroprevalence Linear
B cell epitopes
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