12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase

<p dir="ltr">The purpose of the current study was to evaluate the effect of 12/15- lipoxygenase (12/15-LOX) metabolites on retinal endothelial cell (REC) barrier function. FITC-dextran flux across the REC monolayers and electrical cell-substrate impedance sensing (ECIS) were used to...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Amira Othman (380131) (author)
مؤلفون آخرون:	Saif Ahmad (371052) (author), Sylvia Megyerdi (380132) (author), Rene Mussell (380133) (author), Karishma Choksi (380134) (author), Krishna Rao Maddipati (10950942) (author), Ahmed Elmarakby (380136) (author), Nasser Rizk (380137) (author), Mohamed Al-Shabrawey (380138) (author)
منشور في:	2013
الموضوعات:	Biomedical and clinical sciences Medical biochemistry and metabolomics Ophthalmology and optometry Diabetes mellitus Retina Inflammation Endothelial cells Lipid metabolism Mouse models Vascular permeability Metabolites
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12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase

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