Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model
<p dir="ltr">Advanced oxidation processes (AOPs) have recently attracted great interest in water pollution management. Using the zebrafish embryo model, we investigated the environmental impacts of two thermally (RGOTi)- and hydrogen (H<sub>2</sub>RGOTi)-reduced graphene...
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2019
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| _version_ | 1864513521775017984 |
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| author | Halema Al-Kandari (6316961) |
| author2 | Nadin Younes (4863280) Ola Al-Jamal (11721377) Zain Z. Zakaria (6695093) Huda Najjar (18134101) Farah Alserr (18134104) Gianfranco Pintus (91638) Maha A. Al-Asmakh (17128744) Aboubakr M. Abdullah (1505017) Gheyath K. Nasrallah (9200525) |
| author2_role | author author author author author author author author author |
| author_facet | Halema Al-Kandari (6316961) Nadin Younes (4863280) Ola Al-Jamal (11721377) Zain Z. Zakaria (6695093) Huda Najjar (18134101) Farah Alserr (18134104) Gianfranco Pintus (91638) Maha A. Al-Asmakh (17128744) Aboubakr M. Abdullah (1505017) Gheyath K. Nasrallah (9200525) |
| author_role | author |
| dc.creator.none.fl_str_mv | Halema Al-Kandari (6316961) Nadin Younes (4863280) Ola Al-Jamal (11721377) Zain Z. Zakaria (6695093) Huda Najjar (18134101) Farah Alserr (18134104) Gianfranco Pintus (91638) Maha A. Al-Asmakh (17128744) Aboubakr M. Abdullah (1505017) Gheyath K. Nasrallah (9200525) |
| dc.date.none.fl_str_mv | 2019-03-28T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.3390/nano9040488 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Ecotoxicological_Assessment_of_Thermally-_and_Hydrogen-Reduced_Graphene_Oxide_TiO_sub_2_sub_Photocatalytic_Nanocomposites_Using_the_Zebrafish_Embryo_Model/25378849 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Engineering Chemical engineering Materials engineering reduced graphene oxide/TiO2 nanocomposite photocatalysts zebrafish toxicity LC50 |
| dc.title.none.fl_str_mv | Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Advanced oxidation processes (AOPs) have recently attracted great interest in water pollution management. Using the zebrafish embryo model, we investigated the environmental impacts of two thermally (RGOTi)- and hydrogen (H<sub>2</sub>RGOTi)-reduced graphene oxide/TiO<sub>2</sub> semiconductor photocatalysts recently employed in AOPs. For this purpose, acutoxicity, cardiotoxicity, neurobehavioral toxicity, hematopoietic toxicity, and hatching rate were determinate. For the RGOTi, the no observed effect concentration (NOEC, mortality/teratogenicity score <20%) and the median lethal concentration (LC<sub>50</sub>) were <400 and 748.6 mg/L, respectively. H<sub>2</sub>RGOTi showed a NOEC similar to RGOTi. However, no significant mortality was detected at all concentrations used in the acutoxicity assay (up to1000 mg/L), thus indicating a hypothetical LC<sub>50</sub> higher than 1000 mg/L. According to the Fish and Wildlife Service Acute Toxicity Rating Scale, RGOTi can be classified as “practically not toxic” and H<sub>2</sub>RGOTi as “relatively harmless”. However, both nanocomposites should be used with caution at concentration higher than the NOEC (400 mg/L), in particular RGOTi, which significantly (i) caused pericardial and yolk sac edema; (ii) decreased the hatching rate, locomotion, and hematopoietic activities; and (iii) affected the heart rate. Indeed, the aforementioned teratogenic phenotypes were less devastating in H<sub>2</sub>RGOTi-treated embryos, suggesting that the hydrogen-reduced graphene oxide/TiO<sub>2</sub> photocatalysts may be more ecofriendly than the thermally-reduced ones.</p><p dir="ltr"><br></p><h2>Other Information</h2><p dir="ltr">Published in: Nanomaterials<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/nano9040488" target="_blank">https://dx.doi.org/10.3390/nano9040488</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_6c742fc99aae9095ce09d6db272d01d6 |
| identifier_str_mv | 10.3390/nano9040488 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/25378849 |
| publishDate | 2019 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo ModelHalema Al-Kandari (6316961)Nadin Younes (4863280)Ola Al-Jamal (11721377)Zain Z. Zakaria (6695093)Huda Najjar (18134101)Farah Alserr (18134104)Gianfranco Pintus (91638)Maha A. Al-Asmakh (17128744)Aboubakr M. Abdullah (1505017)Gheyath K. Nasrallah (9200525)EngineeringChemical engineeringMaterials engineeringreduced graphene oxide/TiO2nanocomposite photocatalystszebrafishtoxicityLC50<p dir="ltr">Advanced oxidation processes (AOPs) have recently attracted great interest in water pollution management. Using the zebrafish embryo model, we investigated the environmental impacts of two thermally (RGOTi)- and hydrogen (H<sub>2</sub>RGOTi)-reduced graphene oxide/TiO<sub>2</sub> semiconductor photocatalysts recently employed in AOPs. For this purpose, acutoxicity, cardiotoxicity, neurobehavioral toxicity, hematopoietic toxicity, and hatching rate were determinate. For the RGOTi, the no observed effect concentration (NOEC, mortality/teratogenicity score <20%) and the median lethal concentration (LC<sub>50</sub>) were <400 and 748.6 mg/L, respectively. H<sub>2</sub>RGOTi showed a NOEC similar to RGOTi. However, no significant mortality was detected at all concentrations used in the acutoxicity assay (up to1000 mg/L), thus indicating a hypothetical LC<sub>50</sub> higher than 1000 mg/L. According to the Fish and Wildlife Service Acute Toxicity Rating Scale, RGOTi can be classified as “practically not toxic” and H<sub>2</sub>RGOTi as “relatively harmless”. However, both nanocomposites should be used with caution at concentration higher than the NOEC (400 mg/L), in particular RGOTi, which significantly (i) caused pericardial and yolk sac edema; (ii) decreased the hatching rate, locomotion, and hematopoietic activities; and (iii) affected the heart rate. Indeed, the aforementioned teratogenic phenotypes were less devastating in H<sub>2</sub>RGOTi-treated embryos, suggesting that the hydrogen-reduced graphene oxide/TiO<sub>2</sub> photocatalysts may be more ecofriendly than the thermally-reduced ones.</p><p dir="ltr"><br></p><h2>Other Information</h2><p dir="ltr">Published in: Nanomaterials<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/nano9040488" target="_blank">https://dx.doi.org/10.3390/nano9040488</a></p>2019-03-28T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.3390/nano9040488https://figshare.com/articles/journal_contribution/Ecotoxicological_Assessment_of_Thermally-_and_Hydrogen-Reduced_Graphene_Oxide_TiO_sub_2_sub_Photocatalytic_Nanocomposites_Using_the_Zebrafish_Embryo_Model/25378849CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/253788492019-03-28T03:00:00Z |
| spellingShingle | Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model Halema Al-Kandari (6316961) Engineering Chemical engineering Materials engineering reduced graphene oxide/TiO2 nanocomposite photocatalysts zebrafish toxicity LC50 |
| status_str | publishedVersion |
| title | Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model |
| title_full | Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model |
| title_fullStr | Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model |
| title_full_unstemmed | Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model |
| title_short | Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model |
| title_sort | Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model |
| topic | Engineering Chemical engineering Materials engineering reduced graphene oxide/TiO2 nanocomposite photocatalysts zebrafish toxicity LC50 |